76696-08-7

Upstream product

• 76706-83-7 3,4-O-Isopropyliden-D-threose-trimethylendithioacetal 
• 100-52-7 benzaldehyde 

Downstream Products

• 88481-12-3 (1R)-1,3;4,5-Di-O-isopropyliden-1-C-phenyl-D-xylulose-trimethylendithioacetal 
• 76696-11-2 1,3-Di-O-acetyl-4,5-O-isopropyliden-1-C-(R)-phenyl-D-xylulose-trimethylendithioacetal 

Relevant academic research and scientific papers

Studies on D-Threose Derivatives and on the Preparation of the Olivin Side Chain

Oxidative cleavage of the D-arabinitol derivative 3 yields the dimer 5 of benzylidene D-threose.In pyridine solution D-threose (11), obtained by acid hydrolysis, predominatly represents a mixture of the anomeric furanoses 7 and 12.By either kinetic or thermodynamic isopropylidenation of the trimethylene dithioacetal 9 preparation of the terminal or the non-terminal dioxolane 14 or 16, respectively, is achieved selectively.Starting with 16 several steps lead to the crystalline 4-deoxy-D-threose trimethylene dithioacetal (25), by metallation of which the formation of a trianion could not be demonstrated.However, both the diastereomeric model compounds 28 and 30 of the olivin side chain were prepared via dimetallation of 14.