76711-47-2

Upstream product

• 17642-18-1 methyl bromo-crotonate 
• 136967-11-8 3-tert-butyldimethylsilyloxy-1-acetylcyclohexene trimethylsilyl enol ether 
• 15040-95-6 1-(3-hydroxycyclohex-1-en-1-yl)ethanone 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 76711-55-2 1-[(1S,2R,3R)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-ethanone 
• 136967-11-8 3-tert-butyldimethylsilyloxy-1-acetylcyclohexene trimethylsilyl enol ether 
• 80090-44-4 (1R,2R,3R)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexane-1,1-dicarboxylic acid methyl ester 
• 80090-45-5 (2S,3S)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexane-1,1-dicarboxylic acid dimethyl ester 
• 80090-46-6 (1R,2S,3S)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexane-1,1-dicarboxylic acid ethyl ester methyl ester 
• 80090-59-1 (1R,2S,3S)-2-Butyl-1-(3-ethoxycarbonyl-propyl)-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester 
• 80090-62-6 Toluene-4-sulfonic acid (6R,7S,8S)-7-butyl-2-oxo-1-aza-spiro[5.5]undec-8-yl ester 
• 80090-58-0 (1R,2S,3S)-2-Butyl-1-((E)-3-ethoxycarbonyl-allyl)-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester 
• 80090-56-8 (1R,2S,3S)-1-Allyl-2-butyl-3-hydroxy-cyclohexanecarboxylic acid methyl ester 
• 80090-57-9 (1R,2S,3S)-1-Allyl-2-butyl-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester 
• 84230-35-3 (1R,2R,3S)-2-Butyl-1-(tert-butyl-dimethyl-silanyloxy)-3-(1-trimethylsilanyloxy-vinyl)-cyclohexane 
• 80090-43-3 (1S,2R,3R)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexanecarboxylic acid methyl ester 
• 80090-55-7 (1S,2R,3R)-2-Butyl-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester 
• 80090-54-6 (1R,2S,3S)-2-Butyl-3-hydroxy-cyclohexanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Total Synthesis of (+)-Dihydrocompactin

The total synthesis of (+)-dihydrocompactin 1 has been achieved by employing double Michael reaction of 3-(tert-butyldimethylsiloxy)-1-acetylcyclohexene 13 with methyl crotonate and the TiCl4-promoted aldol condensation of the bis(trimethylsilyl enol ethe

Bicycloannulation of α-Bromo α,β-Unsaturated Esters; Synthesis of the Tricyclo1,5>decane Framework and Its Congeners

Reactions of the kinetic enolates 6 of 1-acetylcyclohexenes 5 with α-bromo α,β-unsaturated esters 7 proceed via a successive Michael-Michael-substitution pathway to give methyl 2-oxotricyclo1,5>decane-5-carboxylates 8 in a one-pot operation.