767351-54-2Relevant academic research and scientific papers
Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17- O, O -bis-sulfamate
Jourdan, Fabrice,Leese, Mathew P.,Dohle, Wolfgang,Hamel, Ernest,Ferrandis, Eric,Newman, Simon P.,Purohit, Atul,Reed, Michael J.,Potter, Barry V. L.
supporting information; experimental part, p. 2942 - 2951 (2010/08/05)
The synthesis and antiproliferative activity of analogues of estradiol 3,17-O,O-bis-sulfamates (E2bisMATEs) are discussed. Modifications of the C-17 substituent reveal that an H-bond acceptor is essential for high antiproliferative activity. The local env
OESTROGEN DERIVATIVES AS INHIBITORS OF STEROID SULPHATASE
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Page 112-113; 104, (2010/02/08)
The present invention provides a compound comprising a steroidal ring system and an optional group R1 selected from any one of -OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wh
