767357-99-3

Upstream product

• 388632-20-0 (-)-(3S)-3-(dibenzylamino)-4-[(tert-butyldimethylsilanyl)oxy]-1-chlorobutan-2-one 
• 100-46-9 benzylamine 
• 591750-70-8 (2S,1'R)-1-benzyl-2-{1'-(dibenzylamino)-2'-[(tert-butyldimethylsilanyl)oxy]ethyl}aziridine 

Downstream Products

• 767358-01-0 (3S,4R,5S)-5-benzylamino-4-dibenzylamino-3-hydroxy-1-propylpiperidine 
• 767357-97-1 (2S,1'R,2'R)-1-benzyl-2-[1'-(dibenzylamino)-2',3'-epoxypropyl]aziridine 
• 767358-00-9 (2S,1'R)-1-benzyl-2-[1'-(dibenzylamino)-2'-oxoethyl]aziridine 

Relevant academic research and scientific papers

Synthesis of chiral amino epoxyaziridines: Useful intermediates for the preparation of chiral trisubstituted piperidines

Chiral aminoalkyl epoxyaziridine 1 is synthesized in high yield and diastereoselectivity from L-serine. Ring opening of epoxyaziridine I with primary amines is carried out with total chemo- and regioselectivity, affording chiral polyfunctionalized piperid