767358-01-0Relevant articles and documents
Synthesis of chiral amino epoxyaziridines: Useful intermediates for the preparation of chiral trisubstituted piperidines
Concellon, Jose M.,Riego, Estela,Rivero, Ignacio A.,Ochoa, Adrian
, p. 6244 - 6248 (2007/10/03)
Chiral aminoalkyl epoxyaziridine 1 is synthesized in high yield and diastereoselectivity from L-serine. Ring opening of epoxyaziridine I with primary amines is carried out with total chemo- and regioselectivity, affording chiral polyfunctionalized piperid