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2β,3β-dihydroxy-5α-cholestan-6-one is a steroidal compound derived from cholesterol, characterized by the presence of two hydroxyl groups at the 2β and 3β positions and a ketone group at the 6 position. This molecule is a key intermediate in the biosynthesis of bile acids, which play a crucial role in the digestion and absorption of dietary fats. It is also involved in the synthesis of other important steroid hormones, such as androgens, estrogens, and progestogens. The structure of 2β,3β-dihydroxy-5α-cholestan-6-one consists of a cyclohexane ring fused to a cyclopentane ring, with a side chain extending from the cyclohexane ring. 2β,3β-dihydroxy-5α-cholestan-6-one is an important target for drug development, as it can be used to modulate the synthesis of various steroid hormones and bile acids, potentially leading to treatments for hormonal imbalances and liver diseases.

7674-78-4

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7674-78-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7674-78-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,7 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7674-78:
(6*7)+(5*6)+(4*7)+(3*4)+(2*7)+(1*8)=134
134 % 10 = 4
So 7674-78-4 is a valid CAS Registry Number.

7674-78-4Relevant academic research and scientific papers

AN ALTERNATIVE ROUTE TO 2α,3α-DIOLS FROM 2,3-UNSATURATED 5α-STEROIDS AVOIDING THE USE OF OSMIUM TETRAOXIDE

Cerny, Vaclav

, p. 2211 - 2217 (2007/10/02)

A method for preparation of 2α,3α-dihydroxy-5α-steroids from 2,3-unsaturated 5α-steroids without the use of OsO4 is described.It involves the sequence of epoxidation, cleavage of the oxirane ring by HI, acetylation, oxidative replacement of iodine by hydroxyl and alkaline hydrolysis (I-IV) without purification of the intermediates.The presence of a 6-keto group does not decrease the yields.The yields are comparable with those obtained by osmylation and the method can find general use, particularly in the synthesis of brassinolide analogs.

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