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2,3-Dihydroxycholestan-6-one is a steroidal compound characterized by the presence of two hydroxyl groups at the 2nd and 3rd carbon positions and a ketone group at the 6th carbon position in its cholestane backbone. This molecule is a derivative of cholestanol, a naturally occurring steroid alcohol, and is involved in various biological processes. It plays a significant role in the synthesis of bile acids and steroid hormones, which are essential for maintaining cholesterol homeostasis and regulating various physiological functions in the body. Due to its structural properties, 2,3-dihydroxycholestan-6-one can also be used as a precursor in the synthesis of other steroidal compounds with potential pharmaceutical applications.

7674-80-8

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7674-80-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7674-80-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,7 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7674-80:
(6*7)+(5*6)+(4*7)+(3*4)+(2*8)+(1*0)=128
128 % 10 = 8
So 7674-80-8 is a valid CAS Registry Number.

7674-80-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,3R,5R,8S,9S,10R,13R,14S,17R)-2,3-dihydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-6-one

1.2 Other means of identification

Product number -
Other names 2alpha,3alpha-Dihydroxy-5alpha-cholestan-6-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7674-80-8 SDS

7674-80-8Downstream Products

7674-80-8Relevant academic research and scientific papers

AN ALTERNATIVE ROUTE TO 2α,3α-DIOLS FROM 2,3-UNSATURATED 5α-STEROIDS AVOIDING THE USE OF OSMIUM TETRAOXIDE

Cerny, Vaclav

, p. 2211 - 2217 (2007/10/02)

A method for preparation of 2α,3α-dihydroxy-5α-steroids from 2,3-unsaturated 5α-steroids without the use of OsO4 is described.It involves the sequence of epoxidation, cleavage of the oxirane ring by HI, acetylation, oxidative replacement of iodine by hydroxyl and alkaline hydrolysis (I-IV) without purification of the intermediates.The presence of a 6-keto group does not decrease the yields.The yields are comparable with those obtained by osmylation and the method can find general use, particularly in the synthesis of brassinolide analogs.

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