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17-oxo-17a-aza-D-homo-5-androsten-3β-yl benzoate is a complex organic compound with the molecular formula C26H33NO3. It is a derivative of the steroidal structure, specifically a 17-oxo steroid, which means it has a carbonyl group (C=O) at the 17th position. The "17a-aza" part of the name indicates the presence of a nitrogen atom replacing a carbon atom at the 17a position, making it an aza-steroid. The "D-homo-5-androsten" portion refers to a structural modification where a carbon atom has been added to the steroid nucleus, specifically at the 5th position, and the "3β-yl" indicates the presence of a hydroxyl group (-OH) at the 3β position. The benzoate group is attached to this steroidal framework, which is a benzoic acid derivative. 17-oxo-17a-aza-D-homo-5-androsten-3β-yl benzoate is of interest in the field of medicinal chemistry, particularly in the development of drugs that target the androgen receptor, and it may have potential applications in the treatment of certain hormonal disorders or cancers.

7675-97-0

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7675-97-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7675-97-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,7 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7675-97:
(6*7)+(5*6)+(4*7)+(3*5)+(2*9)+(1*7)=140
140 % 10 = 0
So 7675-97-0 is a valid CAS Registry Number.

7675-97-0Downstream Products

7675-97-0Relevant academic research and scientific papers

Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams

Dhingra, Neelima,Bhardwaj,Mehta, Neeraj,Mukhopadhyay, Tapas,Kumar, Ashok,Kumar, Manoj

experimental part, p. 2229 - 2236 (2010/06/16)

The 17-oxo-17a-aza-d-homo-5-androsten-3β-yl esters (13-22) were synthesized from commercially available (25R)-5-spirosten-3β-ol (Diosgenin) (6) as starting material. The synthesized compounds were evaluated for their antiproliferative activity, acute toxicity and effect on serum androgen level and were compared with Finasteride as positive controls. Some of the compounds exhibited better cytotoxicity and antiandrogenic activity than the reference control. The detailed synthesis, spectroscopic data and pharmacological screening for the synthesized compounds were reported.

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