76758-10-6Relevant academic research and scientific papers
FORMATION OF 2-ALKYLAMINOOXAZOLES BY THE Rh2(OAc)4-CATALYZED REACTION OF α-DIAZOCARBONYL COMPOUNDS IN THE PRESENCE OF CYANAMIDES
Fukushima, Kazuaki,Ibata, Toshikazu
, p. 149 - 154 (2007/10/02)
The Rh2(OAc)4-catalyzed reaction of α-diazoacetophenones with N,N-dialkylcyanamides gave the corresponding 2-(N,N-dialkylamino)-5-aryloxazoles in high yields.Although para-substituents of the diazoacetophenone and the N-alkyl groups of cyanamide did not a
Synthesis of N-(Tosylmethyl)carbodiimides and Their Application in the Synthesis of 2-Amino-1,3-oxazoles from Aldehydes
Leusen, Albert M. van,Jeuring, Hans J.,Wildeman, Jurjen,Nispen, Simon P. J. M. van
, p. 2069 - 2072 (2007/10/02)
A series of N-(tosylmethyl)carbodiimides (TosCH2N=C=NR1, 3) have been prepared from the corresponding thioureas.Carbodiimides 3 with R1 = triphenylmethyl or tert-butyl are useful synthons in a new one-step synthesis of 2-(alkylamino)-1,3-oxazoles 10 from aromatic aldehydes.Acid-induced removal of the triphenylmethyl group from 10 gives 2-amino-1,3-oxazoles (11).
