7204-48-0

Basic information

• Product Name: 1-TERT-BUTYL-2-THIOUREA
• Synonyms: T-BUTYLTHIOUREA;TERT-BUTYLTHIOUREA;RARECHEM AQ A4 0037;N-(TERT-BUTYL)THIOUREA;1-TERT-BUTYL-2-THIOUREA;1-tert-butylthiourea;tert-Butylthiourea, 98+%;Thiourea,N-(1,1-diMethylethyl)-
• CAS NO: 7204-48-0
• Molecular Formula: C₅H₁₂N₂S
• Molecular Weight: 132.23
• Mol File: 7204-48-0.mol

Chemical Properties

• Melting Point: 171-172°C
• Boiling Point: 187.2±23.0℃ (760 Torr)
• Flash Point: 67.0±22.6℃
• Appearance: /
• Density: 1.028±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.637mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1744506
• CAS DataBase Reference: 1-TERT-BUTYL-2-THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-TERT-BUTYL-2-THIOUREA(7204-48-0)
• EPA Substance Registry System: 1-TERT-BUTYL-2-THIOUREA(7204-48-0)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 7204-48-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
1-TERT-BUTYL-2-THIOUREA is used as an industrial chemical in the production of various chemicals due to its strong, resistive, and chemically reactive nature.
Used in Rubber Production:
1-TERT-BUTYL-2-THIOUREA is used as an accelerator in the vulcanization process for rubber production, enhancing the efficiency and speed of the process.
Used in Agriculture:
1-TERT-BUTYL-2-THIOUREA is used as a growth regulator and fungicide in the agriculture sector, leveraging its strong and chemically reactive properties to promote plant growth and protect crops from fungal infections.

InChI:InChI=1/C5H12N2S/c1-5(2,3)7-4(6)8/h1-3H3,(H3,6,7,8)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 75-64-9 tert-butylamine 
• 22283-39-2 N-benzoyl-N'-t-butylthiourea 
• 590-42-1 tert-butyl isothiocyanate 

Downstream Products

• 301303-40-2 N-(tert-butyl)-4-phenylthiazol-2-amine 
• 1628629-58-2 C₁₃H₁₆N₂O₂S 
• 56954-65-5 3-tert-butyl-2-imino-5,5-diphenylimidazolidin-4-one 
• 1320342-00-4 C₁₄H₁₅F₃N₂OS 
• 735283-16-6 2-(2-tert-butylamino-thiazol-4-yl)-3-cyclohexyl-1-(2-morpholin-4-yl-2-oxo-ethyl)-1H-indole-6-carboxylic acid 
• 76758-16-2 N-tosylmethyl-N'-tert-butylurea 
• 76758-10-6 tert-Butyl-[5-(4-nitro-phenyl)-oxazol-2-yl]-amine 
• 76757-97-6 N-(tosylmethyl)-N'-tert-butylcarbodiimide 
• 76758-12-8 tert-Butyl-[5-(4-methoxy-phenyl)-oxazol-2-yl]-amine 
• 76758-14-0 tert-Butyl-[5-(4-chloro-phenyl)-oxazol-2-yl]-amine 
• 76758-08-2 5-phenyl-2-(tert-butylamino)oxazole 
• 74392-70-4 C₁₂H₁₇ClN₄S*ClH 
• 76758-03-7 N-(tosylmethyl)-N'-tert-butylthiourea 
• 67644-77-3 tert-butyl-(4,5-diphenyl-thiazol-2-yl)-amine 

Relevant articles and documents

Convenient Multicomponent One-Pot Synthesis of 2-Iminothiazolines and 2-Aminothiazoles Using Elemental Sulfur Under Aqueous Conditions

Herein, we present a novel one-pot aqueous reaction for the synthesis of 2-iminothiazolines and 2-aminothiazoles using isocyanides, amines, sulfur, and 2′-bromoacetophenones. The three-component preparation of thioureas is followed by the one-pot cyclization leading to the heterocyclic product. This efficient and mild procedure features excellent step- and atom-economy and enables the chromatography-free preparation of diversely substituted 2-iminothiazoline and 2-aminothiazole derivatives.

Aminothiazole derivatives

The invention relates to aminothiazole heterocyclic derivatives, a preparation method thereof and an application of the aminothiazole heterocyclic derivatives in preparation of drugs for treating or preventing progressive cognitive disorder and/or amnesia diseases.

A convenient and efficient method for the synthesis of mono- and N,N-disubstituted thioureas

A convenient method for the synthesis of mono- and N,N-disubstituted thioureas by the debenzoylation of N-substituted- and N,N-disubstituted- N′-benzoylthioureas with hydrazine hydrate under solvent-free conditions has been developed. N-Substituted-N′-benzoylthioureas and hydrazine hydrate were mixed, and stirred at room temperature without a solvent to give the corresponding N-substituted thioureas in high yields.