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768-19-4

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768-19-4 Usage

General Description

2-Methyl[1,2,4]triazolo[1,5-a]pyridine is a chemical compound with the molecular formula C7H6N4. It is commonly used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. 2-Methyl[1,2,4]triazolo[1,5-a]pyridine has been found to exhibit biological activity, making it a potentially important building block in drug discovery research. Its unique molecular structure and properties make it a valuable tool for chemists and researchers in various fields of science. Studies have shown that this compound has the potential to serve as a scaffold for the development of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 768-19-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 768-19:
(5*7)+(4*6)+(3*8)+(2*1)+(1*9)=94
94 % 10 = 4
So 768-19-4 is a valid CAS Registry Number.

768-19-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methyl-[1,2,4]triazolo[1,5-a]pyridine

1.2 Other means of identification

Product number -
Other names 2-methyl-[1,2,4]triazolo[1,5-a]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:768-19-4 SDS

768-19-4Downstream Products

768-19-4Relevant articles and documents

1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors with a Novel Monodentate Binding Interaction

Ahmed, Saleh,Ayscough, Andrew,Barker, Greg R.,Canning, Hannah E.,Davenport, Richard,Downham, Robert,Harrison, David,Jenkins, Kerry,Kinsella, Natasha,Livermore, David G.,Wright, Susanne,Ivetac, Anthony D.,Skene, Robert,Wilkens, Steven J.,Webster, Natalie A.,Hendrick, Alan G.

supporting information, p. 5663 - 5672 (2017/07/22)

Herein we describe the identification of 4-{[1,2,4]triazolo[1,5-a]pyridin-5-yl}benzonitrile-based inhibitors of the hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme. These inhibitors were shown to possess a novel binding mode by X-ray crystallography, in which the triazolo N1 atom coordinates in a hitherto unreported monodentate interaction with the active site Fe2+ ion, while the benzonitrile group accepts a hydrogen-bonding interaction from the side chain residue of Asn315. Further optimization led to potent PHD-1 inhibitors with good physicochemical and pharmacokinetic properties.

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