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Ebelactone A is a β-lactone enzyme inhibitor that was first isolated from a cultured strain of soil actinomycetes. It possesses the ability to inhibit esterases, lipases, and N-formylmethionine aminopeptidases, which are enzymes found on cell surfaces. This inhibition has been shown to stimulate host defense in immune cells, making Ebelactone A a promising compound for various applications. Additionally, it has been reported to inhibit cutinases produced by fungal pathogens, demonstrating a plant-protective function.

76808-16-7

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76808-16-7 Usage

Uses

Used in Pharmaceutical Industry:
Ebelactone A is used as an enzyme inhibitor for its ability to inhibit esterases, lipases, and N-formylmethionine aminopeptidases. This inhibition can stimulate host defense in immune cells, making it a potential candidate for the development of new therapeutic strategies to enhance the immune response against various diseases.
Used in Agriculture:
Ebelactone A is used as a plant-protective agent for its ability to inhibit cutinases produced by fungal pathogens. This function can help protect plants from infections and diseases, potentially leading to improved crop yields and reduced reliance on chemical pesticides.
Used in Research and Development:
Ebelactone A is used as a research tool for studying the functions and mechanisms of esterases, lipases, and N-formylmethionine aminopeptidases. Understanding the interactions between these enzymes and Ebelactone A can provide valuable insights into their roles in various biological processes and contribute to the development of new drugs and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 76808-16-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,8,0 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76808-16:
(7*7)+(6*6)+(5*8)+(4*0)+(3*8)+(2*1)+(1*6)=157
157 % 10 = 7
So 76808-16-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H34O4/c1-8-12(3)17(21)15(6)18(22)13(4)9-11(2)10-14(5)19-16(7)20(23)24-19/h9,12-17,19,21H,8,10H2,1-7H3/b11-9+/t12-,13-,14+,15+,16+,17-,19+/m1/s1

76808-16-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name EBELACTONE A

1.2 Other means of identification

Product number -
Other names 3,11-DIHYDROXY-2,4,6,8,10,12-HEXAMETHYL-9-OXO-6-TETRADECENOIC ACID 1,3-LACTONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76808-16-7 SDS

76808-16-7Downstream Products

76808-16-7Relevant academic research and scientific papers

Total synthesis of the esterase inhibitor (±)-ebelactone A using an aldol-Claisen strategy

Paterson,Hulme

, p. 7513 - 7516 (2007/10/02)

The β-lactones (±)-ebelactone A has been prepared in 12 steps from diethylketone (9% overall yield) using a series of three boron enolate aldol reactions coupled with the Ireland ester enolate Claisen rearrangement, 10→11.

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