76820-32-1

Basic information

• Product Name: 9a-aza-9a-homo Erythromycin A
• Synonyms: 9a-aza-9a-homo Erythromycin A;(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexaMethyl-11-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-1-o;9a-aza-9a-hoMo ErythroMycin A (~90%)
• CAS NO: 76820-32-1
• Molecular Formula: C37H68N2O13
• Molecular Weight: 748.94142
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 76820-32-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly) Methanol (Slightly)
• CAS DataBase Reference: 9a-aza-9a-homo Erythromycin A(CAS DataBase Reference)
• NIST Chemistry Reference: 9a-aza-9a-homo Erythromycin A(76820-32-1)
• EPA Substance Registry System: 9a-aza-9a-homo Erythromycin A(76820-32-1)

Safety Data

• Hazardous Substances Data: 76820-32-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Novel intermediate of Azithromycin that acts as antibiotic

Upstream product

• 13127-18-9 erythromycin A oxime 

Relevant articles and documents

Erythromycin Series. Part 11. Ring Expansion of Erythromycin A Oxime by the Beckmann Rearrangement

The synthesis of 10-dihydro-10-deoxo-11-azaerythromycin A (11) by the Beckmann rearrangement of erythromycin A oxime (2) and reduction of the imino ether so obtained (5) is described.The structure elucidation of the new ring-expanded semisynthetic erythromycins (5) and (11) has been established on the basis of their analytical and spectral data and acid-catalysed degradation into the aglycones (7) and (13), respectively.Finally, the complete structure of ring-expanded erythronolides (7) and (13) has been determined by X-ray crystallography.