76834-61-2Relevant academic research and scientific papers
Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia
Kumata, Katsushi,Ogawa, Masanao,Takei, Makoto,Fujinaga, Masayuki,Yoshida, Yuichiro,Nengaki, Nobuki,Fukumura, Toshimitsu,Suzuki, Kazutoshi,Zhang, Ming-Rong
, p. 305 - 310 (2012)
Dantrolene (1) is a substrate for breast cancer resistant protein, which is widely distributed in the blood-brain-barrier, intestine, gall bladder, and liver. PET study with 1 labeled with a positron emitter can be used to visualize BCRP and to elucidate
