ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate

Base Information

• Chemical Name: ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate
• CAS No.: 76834-61-2
• Molecular Formula: C₁₅H₁₅N₃O₅
• Molecular Weight: 317.301
• Mol file: 76834-61-2.mol

Synonyms:ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate

Chemical Property of ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate

There total 1 articles about ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

5-(4-nitrophenyl)-2-furaldehyde (7147-77-5) + 2-hydrazinyl acetic acid ethyl ester hydrochloride (6945-92-2) → ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate (76834-61-2)

Guidance literature:

In water; N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2011.10.077

Reference yield: 64.0%

ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate (76834-61-2) + 4-Nitrophenyl chloroformate (7693-46-1) → 4-nitrophenyl 1-(2-ethoxy-2-oxoethyl)-2-[(5-(4-nitrophenyl)furan-2-yl)methylene]hydrazinecarboxylate (1357016-88-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h;

DOI:10.1016/j.bmc.2011.10.077

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + ethyl 2-{2-[5-(4-nitrophenyl)furfurylidene]hydrazino}acetate (76834-61-2) → C16H14ClN3O6 (1357016-91-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 75 ℃; for 0.5h;

DOI:10.1016/j.bmc.2011.10.077

upstream raw materials:

5-(4-nitrophenyl)-2-furaldehyde

2-hydrazinyl acetic acid ethyl ester hydrochloride

Downstream raw materials:

C₁₄H₁₀N₃⁽¹³⁾NO₅

ethyl 2-{1-carbamoyl-2-[(5-(4-nitrophenyl)furan-2-yl)methylene]hydrazinyl}ethanoate

C₁₆H₁₆N₃⁽¹³⁾NO₆

C₁₆H₁₄ClN₃O₆