768383-83-1Relevant academic research and scientific papers
PYRIMIDINE AND QUINOLINE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS
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Page/Page column 23, (2008/06/13)
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutama
Pyrimidine methyl anilines: Selective potentiators for the metabotropic glutamate 2 receptor
Hu, Essa,Chua, Peter C.,Tehrani, Lida,Nagasawa, Johnny Y.,Pinkerton, Anthony B.,Rowe, Blake A.,Vernier, Jean-Michel,Hutchinson, John H.,Cosford, Nicholas D.P.
, p. 5071 - 5074 (2007/10/03)
Pyrimidine methyl anilines as potent and selective mGlu2 potentiators are described. Findings from the structure-activity-relationship investigations are discussed.
