768399-83-3

Upstream product

• 768399-81-1 isopropyl 7-[(2R)-2-(hydroxymethyl)-6-oxopiperidin-1-yl]heptanoate 
• 82302-97-4 dimethyl (3,3-difluoro-2-oxo-3-phenylpropyl)phosphonate 
• 1055985-86-8 C₁₁H₁₂F₂O₄P^(1-)*Na⁽¹⁺⁾ 
• 768399-82-2 C₁₆H₂₇NO₄ 

Downstream Products

• 768399-84-4 isopropyl 7-{(2R)-2-[(1E,3R)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-6-oxopiperidin-1-yl}heptanoate 
• 129145-37-5 (S)-tetrahydro-1-butyl-3,3-diphenyl-1H,3H-pyrrolo{2,1-c}{1,3,2}oxazaborole 

Relevant academic research and scientific papers

EP4 receptor agonist, compositions and methods thereof

This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions, which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.

EP4 receptor agonist, compositions and methods thereof

This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions, which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.