76849-85-9

Basic information

• Product Name: Pyrazine, 2-chloro-5-(4-methoxyphenyl)-
• CAS NO: 76849-85-9
• Molecular Formula: C11H9ClN2O
• Molecular Weight: 220.658
• Mol File: 76849-85-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrazine, 2-chloro-5-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2-chloro-5-(4-methoxyphenyl)-(76849-85-9)
• EPA Substance Registry System: Pyrazine, 2-chloro-5-(4-methoxyphenyl)-(76849-85-9)

Safety Data

• Hazardous Substances Data: 76849-85-9(Hazardous Substances Data)

Upstream product

• 1076-95-5 p-methoxyphenylglyoxal 
• 19745-07-4 2,5-dichloropyrazine 
• 696-62-8 para-iodoanisole 
• 93296-09-4 4-methoxyphenylzinc chloride 
• 7646-85-7 zinc(II) chloride 
• 76849-79-1 5-(4-methoxyphenyl)-2(1H)-pyrazinone 

Downstream Products

• 1174517-54-4 (3-chloro-6-(4-methoxyphenyl)pyrazin-2-yl)(phenyl)methanone 
• 76849-83-7 5-(4-Methoxy-phenyl)-4-oxy-1H-pyrazin-2-one 
• 76849-90-6 1-Hydroxy-5-(4-methoxy-phenyl)-1H-pyrazin-2-one 

Relevant articles and documents

Regio- And chemoselective multiple functionalization of chloropyrazine derivatives. Application to the synthesis of coelenterazine

Successive regio- and chemoselective metalations of chloropyrazines using TMPMgCl-LiCl and TMPZnCIIiCI furnish, after trapping with electrophiles, highly functionalized pyrazines in high yields. Application to a synthesis of coelenterazine, a bioluminescent natural product in jellyfish Aequorea victoria, in nine steps (9% overall yield) is reported.