76862-10-7

Upstream product

• 5680-79-5 glycine ethyl ester hydrochloride 
• 104-87-0 4-methyl-benzaldehyde 
• 616-34-2 methoxycarbonylmethylamine 

Downstream Products

• 76862-14-1 (E)-3-Dimethylamino-2-{[1-p-tolyl-meth-(E)-ylidene]-amino}-acrylic acid methyl ester 
• 939799-29-8 methyl (1S,3R,3aS,6aR)-4,6-dioxo-3-(p-methylphenyl)-5-phenyl-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 1169983-13-4 methyl (1R,3S,3aR,6aS)-4,6-dioxo-3-(p-methylphenyl)-5-phenyl-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate 
• 1202065-83-5 2-methyl (2S,3R,4S,5R)-4-benzoyl-5-(4-methylphenyl)-3-phenyl-2-pyrrolidinecarboxylate 

Relevant academic research and scientific papers

Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions

In dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent-bond formation and breaking in a dynamic process enables the interconversion of products formed under kinetic control to thermod

Switching Diastereoselectivity in Catalytic Enantioselective (3+2) Cycloadditions of Azomethine Ylides Promoted by Metal Salts and Privileged Segphos-Derived Ligands

Catalytic enantioselective 1,3-dipolar cycloaddition between imino esters and electrophilic alkenes, employing chiral metal complexes derived from copper(I) and silver(I) salts and (S)-DM-or (S)-DTBM-Segphos as ligands produces diastereodivergently exo-or

Axially chiral BINIM and Ni(II)-catalyzed highly enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides and N-arylmaleimides

(Chemical Equation Presented) Axially chiral BINIM-Ni(II) complexes are effective catalysts in the asymmetric 1,3-dipolar cycloaddition reactions of azomethine ylides and N-arylmaleimides to give the corresponding adducts in good yields and up to 95% enan

Chiral thiophosphoramide and selenophosphoramide ligands in the Cu(I)-promoted catalytic enantioselective 1,3-dipolar cycloaddition reactions of azomethine ylides and pyrrole-2,5-dione derivatives

Chiral C2-symmetric diphenylthiophosphoramide ligand L1 prepared from C2-symmetric (1S,2S)-(-)-1,2-diphenylethylenediamine was found to be a fairly effective chiral ligand for Cu(I)-promoted 1,3-dipolar cycloaddition of imines and py

Cu(I)-catalyzed highly exo-selective and enantioselective [3 + 2] cycloaddition of azomethine ylides with acrylates

(Chemical Equation Presented) A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.

A convenient procedure for the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides and alkenes

(Chemical Equation Presented) Silver fluoride and cinchona alkaloids catalyze the diastereo- and enantioselective 1,3-dipolar cycloaddition between azomethine ylides, generated from N-alkylideneglycine esters, and acrylates to give the corresponding endo-adducts. Azomethine ylides derived from aromatic and aliphatic aldehydes react in a highly diastereoselective reaction with good yields and enantioselectivities of the substituted pyrrolidines.