76867-83-9

Basic information

• Product Name: Morpholine, 4-[S-methyl-N-(4-methylphenyl)sulfonimidoyl]-
• CAS NO: 76867-83-9
• Molecular Formula: C12H18N2O2S
• Molecular Weight: 254.353
• Mol File: 76867-83-9.mol

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-[S-methyl-N-(4-methylphenyl)sulfonimidoyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-[S-methyl-N-(4-methylphenyl)sulfonimidoyl]-(76867-83-9)
• EPA Substance Registry System: Morpholine, 4-[S-methyl-N-(4-methylphenyl)sulfonimidoyl]-(76867-83-9)

Safety Data

• Hazardous Substances Data: 76867-83-9(Hazardous Substances Data)

Upstream product

• 19977-37-8 methanesulfinic acid 4-methyl-anilide 
• 110-91-8 morpholine 
• 89278-81-9 C₈H₁₀ClNOS 

Downstream Products

• 157734-20-8 N-(p-tolyl)-3-hydroxy-3-phenylpropanesulfonimidomorpholide 
• 157734-21-9 C₂₆H₄₀N₂O₃SSi 
• 157734-26-4 C₂₅H₃₇ClN₂O₃SSi 
• 622-57-1 N-ethyl-p-tolylamine 
• 115204-39-2 2-hydroxy-2,2-diphenyl-N-p-tolylethanesulfonimidmorpholide 

Relevant articles and documents

Synthesis and Reaction of Diaminosulfoxonium Salts

Diaminosulfoxonium salts were prepared by alkylation of sulfonimidamides.Their physical properties were described.Their reaction with bases gave the corresponding ylides and sulfonimidamides.The intramolecular rearrangement of the ylides led to ortho substitution via intermediate cyclohexadienimines.Hydrogen transfer, accompanying rearomatization and the subsequent action of bases gave dihydro-2,1-benzisothiazole derivatives.These ylides were also found to react with aldehydes to afford epoxides in moderate yields.

Reaction of sulfonimidamide Anions with Electrophiles

The reaction of alkylsulfonimidamides with bases gave corresponding carboanions, which were allowed to react with carbonyl compounds to give (2-hydroxyalkyl)sulfonimidamides in good yields.When benzoic anhydride or chlorotrimethylsilane was treated with these anions, corresponding phenacylsulfonimidamides or (trimethylsilyl)methylsulfonimidamides were obtained.On the other hand, the reaction of methyl N-p-tosylsulfonimidmorpholide anion with carbonyl compounds afforded epoxides or oxetanes in good yields.

SYNTHESES AND REACTIONS OF DIAMINOOXOSULFONIUM SALTS

Diaminooxosulfonium salts were prepared by alkylation of aminosulfoximines.Their reactions with dimsyl sodium gave the corresponding ylides and sulfoximines.The intramolecular rearrangement of the ylide led to ortho substitution via an intermediate cyclohexadienoneimine.Hydrogen transfer, accompaning rearomatization and the subsequent action of a base gave a dihydrobenzoisothiazole derivative.