76887-37-1

Basic information

• Product Name: 4-(3-nitro-1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-pyrimedin-2(1H)-one
• Synonyms: 4-(3-nitro-1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-pyrimedin-2(1H)-one
• CAS NO: 76887-37-1
• Molecular Weight: 466.364
• Mol File: 76887-37-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-nitro-1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-pyrimedin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-nitro-1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-pyrimedin-2(1H)-one(76887-37-1)
• EPA Substance Registry System: 4-(3-nitro-1,2,4-triazol-1-yl)-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-pyrimedin-2(1H)-one(76887-37-1)

Safety Data

• Hazardous Substances Data: 76887-37-1(Hazardous Substances Data)

Upstream product

• 74257-00-4 1-(mesitylene-2-sulfonyl)-3-nitro-1H-1,2,4-triazole 
• 4105-38-8 Tri-O-acetyluridine 

Downstream Products

• 65-46-3 CYTIDINE 

Relevant articles and documents

REACTION BETWEEN 1-ARENESULPHONYL-3-NITRO-1,2,4-TRIAZOLES AND NUCLEOSIDE BASE RESIDUES. ELUCIDATION OF THE NATURE OF SIDE-REACTIONS DURING OLIGONUCLEOTIDE SYNTHESIS.

The protected guanosine and uridine derivatives (3a, 3b, and 4) react with 1-(mesitylene-2-sulphonyl)-3-nitro-1,2,4-triazole (MSNT, 2a) to give 5a, 5b and 7, respectively; 9 is converted into 10 in the same way.The reactions proceed more rapidly in the presence of diphenyl phosphate.