769-37-9

Basic information

• Product Name: Benzene, 1-chloro-2,3,4,5-tetrafluoro-
• CAS NO: 769-37-9
• Molecular Formula: C6HClF4
• Molecular Weight: 184.521
• Mol File: 769-37-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-2,3,4,5-tetrafluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-2,3,4,5-tetrafluoro-(769-37-9)
• EPA Substance Registry System: Benzene, 1-chloro-2,3,4,5-tetrafluoro-(769-37-9)

Safety Data

• Hazardous Substances Data: 769-37-9(Hazardous Substances Data)

Upstream product

• 715-30-0 1-chloro-2,3,4,5-tetrafluoro-6-trifluoromethyl-benzene 
• 1074-91-5 1-bromo-2,3,4,5-tetrafluorobenzene 
• 5121-89-1 1-iodo 2,3,4,5-tetrafluoro benzene 
• 344-07-0 1-chloro-2,3,4,5,6-pentafluorobenzene 
• 75-77-4 chloro-trimethyl-silane 
• 1198-59-0 1,2-dichloro-3,4,5,6-tetrafluorobenzene 
• 551-62-2 1,2,3,4-tetrafluorobenzene 

Downstream Products

• 551-62-2 1,2,3,4-tetrafluorobenzene 
• 2708-97-6 5,6-diiodo-1,2,3,4-tetrafluorobenzene 
• 591249-21-7 2,3,4,5-tetrafluorobenzenesulfonyl chloride 
• 1868-80-0 2-chlorotetrafluorobenzoic acid 
• 1428-08-6 1-chloro-2,3,4,5-tetrafluoro-6-iodo-benzene 

Relevant articles and documents

Transition-Metal-Free Catalytic Hydrodefluorination of Polyfluoroarenes by Concerted Nucleophilic Aromatic Substitution with a Hydrosilicate

A transition-metal-free catalytic hydrodefluorination (HDF) reaction of polyfluoroarenes is described. The reaction involves direct hydride transfer from a hydrosilicate as the key intermediate, which is generated from a hydrosilane and a fluoride salt. The eliminated fluoride regenerates the hydrosilicate to complete the catalytic cycle. Dispersion-corrected DFT calculations indicated that the HDF reaction proceeds through a concerted nucleophilic aromatic substitution (CSNAr) process.

Reactions of polyfluoroaromatic compounds with electrophilic agents in the presence of tris(dialkylamino)phosphine: 6. * Reactions of halogenotetrafluorobenzenes RC6F4X (X = Cl, Br, or I) with chlorotrimethylsilane

The rate of replacement of the halogen atom in isomers of RC6F4X (X = Cl, Br, or I) by the SiMe3 group under the action of Me3SiCl and P(NEt2)3 depends on the nature and the mutual arrangement of the substituents X and R. In addition to silyldehalogenation, compounds C6HF4X (X = Br or I) undergo silyldeprotonation and reduction to tetrafluorobenzenes.