769-51-7

Basic information

• Product Name: 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID
• Synonyms: 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID;2-Amino-4-methyl-pyrimidine-5-carboxylic acid ,97%;2-amino-4-methyl-5-pyrimidinecarboxylic acid(SALTDATA: FREE);2-amino-4-methyl-5-pyrimidinecarboxylic acid;5-Carboxy-4-methylpyrimidin-2-amine;2-Amino-4-methylpyrimidine-5-carboxylicacid95%
• CAS NO: 769-51-7
• Molecular Formula: C₆H₇N₃O₂
• Molecular Weight: 153.14
• Product Categories: pharmacetical;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines
• Mol File: 769-51-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 313-316 °C (decomp)
• Boiling Point: 452.2oC at 760 mmHg
• Flash Point: 227.3oC
• Appearance: /
• Density: 1.431g/cm3
• Vapor Pressure: 5.75E-09mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C
• PKA: 2.03±0.25(Predicted)
• CAS DataBase Reference: 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID(769-51-7)
• EPA Substance Registry System: 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID(769-51-7)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-37/38-48
• Safety Statements: 7/8-22-26-36/37/39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 769-51-7(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

InChI:InChI=1/C6H7N3O2/c1-3-4(5(10)11)2-8-6(7)9-3/h2H,1H3,(H,10,11)(H2,7,8,9)

Upstream product

• 134653-70-6 ethyl 2-[(dimethylamino)methylene]-3-oxobutanoate 
• 81633-29-6 2-amino-4-methylpyrimidine-5-carboxylic acid ethyl ester 

Downstream Products

• 1258197-07-7 C₂₄H₃₀ClN₉O₂ 
• 1258197-20-4 C₁₃H₁₃ClN₄O 
• 108-52-1 4-Methyl-pyrimidin-2-ylamin 

Relevant articles and documents

cGAS ANTAGONIST COMPOUNDS

Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS

The present invention comprises inter alia triazine compounds as shown in formula (I) and pharmaceutically acceptable salts thereof.

Direction of hydrolysis of esters of some pyrimidine-5-carboxylic acids

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