76905-13-0

Basic information

• Product Name: (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester
• CAS NO: 76905-13-0
• Molecular Weight: 346.303
• Mol File: 76905-13-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(76905-13-0)
• EPA Substance Registry System: (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester(76905-13-0)

Safety Data

• Hazardous Substances Data: 76905-13-0(Hazardous Substances Data)

Upstream product

• 20445-31-2 R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid 
• 599-04-2 (R)-Pantolacton 
• 1196498-52-8 2(R)-hydroxy-3,3-dimethyl-4-oxo-butxyric acid ethyl ester 

Relevant articles and documents

Histidine-catalyzed asymmetric aldol addition of enolizable aldehydes: Insights into its mechanism

Extensive studies of asymmetric cross-aldol addition between enolizable aldehydes are described and provide a deeper insight into histidine-catalyzed aldol additions. In particular, aspects of enantio- as well as diastereoselectivity of these reactions are discussed. Rules and predictions of configurative outcome are explained by using different transition-state models. These discussions are confirmed by extensive computations.