769119-29-1

Upstream product

• 1194-02-1 4-fluorobenzonitrile 
• 1087161-30-5 methyl 4-((1-cyclobutylpiperidin-4-yl)oxy)benzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 869224-62-4 1-cyclobutyl-4-piperidinol 
• 397275-27-3 4-((1-cyclobutylpiperidin-4-yl)oxy)benzonitrile 
• 685565-26-8 4-(4-piperidinyloxy)benzonitrile trifluoroacetate 
• 333954-86-2 4-(4-cyano phenoxy)piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 870997-68-5 4-((1-cyclobutylpiperidin-4-yl)oxy)benzaldehyde 
• 1087161-30-5 methyl 4-((1-cyclobutylpiperidin-4-yl)oxy)benzoate 

Relevant academic research and scientific papers

Benzamide derivatives and their constrained analogs as histamine H3 receptor antagonists

A series of 4-(1-substituted piperidin-4-yloxy) benzamides and 6-(1-substituted piperidin-4-yloxy)-3,4-dihydro-2H-isoquinolin-1-one derivatives have been synthesized and tested for their binding affinity towards H3 receptor. Most of these synth

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.