769135-97-9Relevant academic research and scientific papers
Design and synthesis of a nitrogen mustard derivative stabilized by apo-neocarzinostatin
Urbaniak, Michael D.,Bingham, John P.,Hartley, John A.,Woolfson, Derek N.,Caddick, Stephen
, p. 4710 - 4715 (2004)
Neocarzinostatin (NCS) is an antitumor antibiotic comprising a 1:1 protein-chromophore complex and exhibits cytotoxic action through DNA cleavage via H-abstraction. Cytotoxic activity resides with the chromophore 1 alone, while the protein (apoNCS) protec
