769154-38-3Relevant academic research and scientific papers
Nickel-catalyzed: Syn -stereocontrolled ring-opening of oxa- and azabicyclic alkenes with dialkylzinc reagents
Deng, Yingying,Yang, Wen,Yao, Yongqi,Yang, Xin,Zuo, Xiongjun,Yang, Dingqiao
, p. 703 - 711 (2019/01/24)
A new nickel-catalyzed syn-stereocontrolled ring-opening of oxa- and azabicyclic alkenes with dialkylzinc reagents was developed, which afforded the corresponding cis-2-alkyl-1,2-dihydronaphthalen-1-ols and 1,2-alkyl amide derivatives in moderate to excellent yields (up to 99% yield) under mild conditions. In this work, we successfully avoided obtaining hydride addition byproducts arising from β-hydride elimination on an ethyl nickel species. Furthermore, a plausible mechanism for the ring-opening reaction was also proposed.
Copper-catalyzed asymmetric ring-opening reaction of oxabenzonorbornadienes with Grignard and aluminum reagents
Millet, Renauds,Gremaud, Ludovic,Bernardez, Tania,Palais, Laetitia,Alexakis, Alexandre
experimental part, p. 2101 - 2112 (2009/12/31)
A highly enantioselective method for the copper-catalyzed desymmetrization of oxabenzonorbornadienes with aluminum reagents and SimplePhos as chiral ligand has been developed. The same reaction with Grignard reagents is also reported. A wide range of alky
Transition metal complexes of fesulphos ligands in enantioselective catalytic transformations
Arrayas, Ramon Gomez,Mancheno, Olga Garcia,Cabrera, Silvia,Carretero, Juan Carlos
, p. 1259 - 1265 (2007/10/03)
Metal complexes of 1-phosphino-2-sulfenylferrocene (fesulphos ligands) act as highly efficient catalysts in Pd-catalyzed desymmetrization of meso heterobicyclic alkenes and in Cu-catalyzed formal aza Diels-Alder reaction of Danishefsky diene to N-sulfonyl
Fesulphos-palladium(II) complexes as well-defined catalysts for enantioselective ring opening of meso heterobicyclic alkenes with organozinc reagents
Cabrera, Silvia,Arrayas, Ramon Gomez,Alonso, Ines,Carretero, Juan C.
, p. 17938 - 17947 (2007/10/03)
The air-stable and readily available cationic methyl palladium(II) complexes of planar chiral Fesulphos ligands [(Fesulphos)Pd(Me)(PhCN)] + X- are highly efficient catalysts for the alkylative ring opening of oxa- and azabicyclic alk
Cationic planar chiral palladium P,S complexes as highly efficient catalysts in the enantioselective ring opening of oxa- and azabicyclic alkenes
Cabrera, Silvia,Gomez Arrayas, Ramon,Carretero, Juan C.
, p. 3944 - 3947 (2007/10/03)
Open plan: Cationic methylpalladium(II) complexes of planar chiral Fesulphos ligands (Fesulphos = 1-phosphanyl-2-sulfenylferrocene) show excellent performance in the alkylative ring opening of oxa- and azabicyclic alkenes with dialkyl zinc reagents (see s
Copper phosphoramidite catalyzed enantioselective ring-opening of oxabicyclic alkenes: Remarkable reversal of stereocontrol
Bertozzi, Fabio,Pineschi, Mauro,Macchia, Franco,Arnold, Leggy A.,Minnaard, Adriaan J.,Feringa, Ben L.
, p. 2703 - 2705 (2007/10/03)
An unprecedented copper phosphoramidite catalyzed enantioselective alkylative ring-opening reaction of oxabenzonorbornadiene derivatives with dialkylzinc reagents is reported. The reaction shows high levels of anti-stereoselectivity (up to anti/syn >99:1), complementary to the Pd(0)-catalyzed syn-selective ring-opening protocol, allowing a new entry to anti-dihydronaphthols with high enantioselectivity (up to 99% ee).
