76926-84-6

Upstream product

• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 64-19-7 acetic acid 
• 82045-04-3 (rac)-(E)-2-acetoxy-4-phenylbut-3-ene 
• 13505-39-0 3-hydroxy-1-phenyl-butan-1-one 
• 108-24-7 acetic anhydride 

Downstream Products

• 13505-39-0 3-hydroxy-1-phenyl-butan-1-one 

Relevant academic research and scientific papers

One-Pot Preparation of Alcohols from Aromatic Olefins and Acrylic Acid Derivatives by Cobalt(II) Porphyrin-Catalyzed Reductive Oxygenation Followed by Reduction with Trimethyl Phosphite

Various aromatic olefins and acrylic acid derivatives were converted to benzyl alkohols and α-hydroxyalkanoic acid derivatives in good yields by the reductive oxygenation with oxygen and triethylsilane in the presence of catalytic amount of cobalt(II) porphyrin followed by treating the reaction mixture with trimethyl phosphite.

Cobalt(II) Chloride Catalyzed Acylation of Alcohols with Acetic Anhydride: Scope and Mechanism

Cobalt(II) chloride catalyzes the acetylation of a variety of alcohols with acetic anhydride in excellent yield.Primary hydroxyl groups can be selectively acylated in the presence of secondary and tertiary ones while the secondary hydroxyl groups can be preferentially acetylated in the presence of tertiary ones.Tertiary alcohols have been found to give ketones, acetoacetates, olefins, and diketene in addition to the acetate.The β-hydroxy esters and ketones can be acylated under these conditions without any elimination, and this reaction has been compared with 4-(dimethylamino)pyridine (DMAP)-mediated acylations where elimination of the resulting β-acetoxy carbonyl compound is observed.A detailed investigation of the acylation of tertiary alcohols has revealed that these reactions proceed via a tertiary alkoxy radical and ketene.A mechanism for these acylations is proposed by invoking an electron-transfer process.

Palladium(II)-catalyzed Alkoxylation and Acetoxylation of Alkenes

Addition of alcohols or acetic acid to alkenes activated by carbonyl or acetal is catalyzed by PdCl2(MeCN)2 to give the corresponding ethers and esters.