7693-44-9

Basic information

• Product Name: 4-BROMOPHENYL CHLOROFORMATE
• Synonyms: 4-BROMOPHENYL CHLOROFORMATE;4-Bromophenyl chloroformate, 95+%;4-BroMophenyl carbonochloridate;p-Bromophenyl chloroformate
• CAS NO: 7693-44-9
• Molecular Formula: C₇H₄BrClO₂
• Molecular Weight: 235.46
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 7693-44-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 118 °C12 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /Low Melting Solid or Liquid
• Density: 1.648 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0318mmHg at 25°C
• Refractive Index: n20/D 1.5575(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-BROMOPHENYL CHLOROFORMATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMOPHENYL CHLOROFORMATE(7693-44-9)
• EPA Substance Registry System: 4-BROMOPHENYL CHLOROFORMATE(7693-44-9)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-34
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 3277 6.1/PG 2
• WGK Germany: 3
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 7693-44-9(Hazardous Substances Data)

Usage

Uses

4-Bromophenyl Chloroformate is a useful organic building block.

InChI:InChI=1/C7H4BrClO2/c8-5-1-3-6(4-2-5)11-7(9)10/h1-4H

Upstream product

• 106-41-2 4-bromo-phenol 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 75-44-5 phosgene 

Downstream Products

• 14733-73-4 5-bromo-1,3-benzoxazol-2(3H)-one 
• 1620228-50-3 4-bromophenyl 5-fluoroisoindoline-2-carboxylate 
• 1620228-54-7 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl 5-((4-methylpiperazin-1-yl)methyl)isoindoline-2-carboxylate 
• 1620228-51-4 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl 5-fluoroisoindoline-2-carboxylate 
• 1620228-49-0 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl 5-methoxyisoindoline-2-carboxylate 
• 1620228-47-8 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl 3-phenylpyrrolidine-1-carboxylate 
• 1620228-45-6 (4-((isoindoline-2-carbonyl)oxy)phenyl)boronic acid 
• 1620223-06-4 4-(4-oxo-3,4-dihydrophthalazin-1-yl)phenyl 3-phenylpyrrolidine-1-carboxylate 
• 1620228-44-5 4-bromophenyl isoindoline-2-carboxylate 
• 1620228-52-5 4-bromophenyl 5-((4-methylpiperazin-1-yl)methyl)isoindoline-2-carboxylate 
• 1620228-48-9 4-bromophenyl 5-methoxyisoindoline-2-carboxylate 

Relevant articles and documents

Visible-Light-Induced Intramolecular C(sp2)-H Amination and Aziridination of Azidoformates via a Triplet Nitrene Pathway

Catalytic intramolecular C-H amination and aziridination reactions of o-allylphenyl azidoformates have been achieved under visible-light irradiation, providing a mild, clean, and efficient method for the synthesis of useful benzoxazolones and [5.1.0] bicyclic aziridines. Mechanistic studies suggest that a triplet nitrene acts as the reactive intermediate. The chemoselectivity of the reaction, with alkyl olefin aziridination ? electron deficient olefin aziridination ≈ C(sp2)-H amination ? C(sp3)-H amination was observed, which may be instructive in the development of an understanding of visible-light-induced triplet nitrene transformation reactions.

1-Aziridine carboxylic acid derivatives with immunostimulant activity

2-Substituted-1-aziridine-carboxylic acid esters exhibiting immuno-stimulant activity and of the formula STR1 wherein X is a carbamoyl or alkoxycarbonyl radical, and R1 is an aliphatic hydrocarbon radical optionally substituted by halogen, alkoxy, amino, carbamoyloxy, cycloalkyl, hydroxyl, an imido or heterocyclic radical, cycloalkyl; or aryl, aralkyl, aryloxyalkyl or arylthioalkyl wherein the aryl moiety is optionally substituted by halogen, alkyl, alkoxy, hydroxyl, amino, nitro, cyano, acyl, carbalkoxy, thioalkyl, alkylsulphonyl, phenyl or trifluoromethyl. Counterparts where X is --CN and R1 is as above, except for ethyl, are also new.