76943-18-5

Basic information

• Product Name: [(2,2,2-trifluoroethoxy)sulfanyl]benzene
• CAS NO: 76943-18-5
• Molecular Formula: C₈H₇F₃OS
• Molecular Weight: 208.2008
• Mol File: 76943-18-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 198.3°C at 760 mmHg
• Flash Point: 73.7°C
• Density: 1.3g/cm³
• Vapor Pressure: 0.51mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: [(2,2,2-trifluoroethoxy)sulfanyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [(2,2,2-trifluoroethoxy)sulfanyl]benzene(76943-18-5)
• EPA Substance Registry System: [(2,2,2-trifluoroethoxy)sulfanyl]benzene(76943-18-5)

Safety Data

• Hazardous Substances Data: 76943-18-5(Hazardous Substances Data)

Usage

General Description

[(2,2,2-trifluoroethoxy)sulfanyl]benzene is a chemical compound consisting of a benzene ring with a sulfur atom bonded to an ethoxy group that is, in turn, attached to three fluorine atoms. It is a colorless liquid with a slightly sweet odor and is used as a solvent and as a precursor in the synthesis of other organic compounds. The compound has potential applications in pharmaceuticals, agrochemicals, and materials science due to its unique chemical structure and properties. Additionally, it is important to handle this compound with caution as it may be hazardous if not properly used and stored.

Upstream product

• 882-33-7 diphenyldisulfane 
• 75-89-8 2,2,2-trifluoroethanol 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 71181-76-5 pentakis(2,2,2-trifluoroethoxy)phosphorane 
• 76943-20-9 thiophenyltetrakis(2,2,2-trifluoroethoxy)phosphorane 
• 76943-21-0 diphenyltris(2,2,2-trifluoroethoxy)phosphorane 
• 16599-17-0 2,2'-diphenyl-1,1'-ethane-1,2-diyl-bis-disulfane 

Relevant articles and documents

The kinetics and mechanism of the reaction of tricoordinate phosphorus compounds with sulfenate esters

The kinetics and mechanism of the reaction of tricoordinate phosphorus compounds, ArnP(OCH2CF3)3-n with arylsulfenate esters, ArSOCH2CF3, are reported. Product analysis, kinetic order, activation parameters, Hammett data and solvent effects are the criteria used to elucidate the two step mechanism involving arylthiophosphoranes as intermediates.

INHIBITION OF PSEUDOROTATION IN SOME MONOCYCLIC PENTAOXYPHOSPHORANES

Phosphoranes were prepared by allowing 2,4,8,10-tetra-tert-butyl-6-(2,2,2-trifluoroethoxy)-12H-dibenzodioxaphosphocin, the analogous ethoxy compound, 2,4,8,10-tetra-tert-butyl-6-(2,2,2-trifluoroethoxy)-dibenzodioxaphosphepin and the analogous compound without tert-butyl groups to react with trifluoroethyl benzenesulfonate.The first three phosphoranes showed significant barriers to intramolecular ligand reorganization, 14-16 kcal/mole.The phosphorane without the tert-butyl groups had a barrier too low to measure.These observations are discussed in terms of steric inhibition of pseudorotation.