76943-47-0

Usage

Uses

Used in Pharmaceutical Research and Development:
Pyrazolo[1,5-a]pyridin-2-ylmethanol is used as a building block in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs with antimicrobial, anti-inflammatory, and antiviral properties.
Used in Antimicrobial Applications:
Pyrazolo[1,5-a]pyridin-2-ylmethanol is used as an antimicrobial agent, leveraging its ability to combat various microorganisms, which makes it a valuable component in the development of new antibiotics and antimicrobial therapies.
Used in Anti-inflammatory Applications:
Pyrazolo[1,5-a]pyridin-2-ylmethanol is used as an anti-inflammatory agent, potentially aiding in the treatment of conditions characterized by inflammation by modulating the body's inflammatory response.
Used in Antiviral Applications:
Pyrazolo[1,5-a]pyridin-2-ylmethanol is used as an antiviral agent, showing promise in the development of treatments for viral infections by inhibiting viral replication or other stages of the viral life cycle.
Used in Drug Treatment for Various Diseases:
Pyrazolo[1,5-a]pyridin-2-ylmethanol is used as a potential drug candidate for the treatment of various diseases, highlighting its importance in biomedical research and development for its therapeutic potential across a range of medical conditions.

InChI:InChI=1/C8H8N2O/c11-6-7-5-8-3-1-2-4-10(8)9-7/h1-5,11H,6H2

Upstream product

• 63237-88-7 pyrazolo[1,5-a]pyridine-2-carboxylic acid 
• 63237-87-6 pyrazolo[1,5-a]pyridine-2,3-dicarboxylic acid 
• 5825-71-8 pyrazolo<1,5-a>pyridine-2,3-dicarboxylic acid dimethyl ester 
• 25275-41-6 N-iminopyridinium ylide 
• 110-86-1 pyridine 
• 76943-44-7 2,4,6-Trimethyl-benzenesulfonate1-amino-2-(3-hydroxy-prop-1-ynyl)-pyridinium; 

Downstream Products

• 885275-10-5 pyrazolo[1,5-a]pyridine-2-carbaldehyde 
• 1201688-43-8 2-(1-methyl-4-phenyl-1H-imidazol-2-ylsulfanylmethyl)-pyrazolo[1,5-a]pyridine 

Relevant academic research and scientific papers

COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).

VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL INHIBITOR

A compound represented by the following General Formula (I), a tautomer or a stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, is used as a voltage-dependent T-type calcium channel blocker: wherein A represents a fused ring which may have a substituent, the fused ring being composed of a 5-membered heteroaryl group or a 5-membered or 6-membered heterocyclic ring and a benzene ring or the like, the 5-membered heteroaryl group having one to three identical or different heteroatoms as a ring-constituting element(s) having at least one substituent such as an alkoxy group having 1 to 8 carbon atoms and substituted with 1 to 5 halogen atoms; R represents a hydrogen atom or the like; B represents CR5(Q1) or NQ2, herein Q1 represents a benzimidazole group which may have a substituent; Q2 represents an alkyl group having 1 to 8 carbon atoms which may have a substituent, a heteroaryl group which may have a substituent, or the like; R0, R1, R2, R3, R4, and R5 each represent a hydrogen atom or the like; and n and m each represent 0, 1, or 2, provide that n and m are not 0 and 2 at the same time.

SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel spiro-oxadiazoline compounds that are suitable as agonists or partial agonists of a7-nAChR, and pharmaceutical compositions of the same, methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering a spiro-oxadiazoline cx7-nAChR agonist or partial agonist, to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

Substituted pyrazolo[1,5-a]pyridines, their preparation and use as medicaments

The present invention relates to new substituted pyrazolo[1,5-a]pyridine having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.

SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINES, THEIR PREPARATION AND USE AS MEDICAMENTS

The present invention relates to new substituted pyrazolo[1,5-a]pyridine having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.

3-aminopyrazolo heterocyclic derivatives, and use for colorimetric determinations

The present invention is concerned with the use of certain 3-aminopyrazolo-heterocyclic compounds for the colorimetric determination of hydrogen peroxide, hydrogen peroxide-forming systems, peroxidase, peroxidate-active substances and electron-rich aromatic compounds. The present invention is also concerned with corresponding processes of determination and with agents appropriate therefor. Furthermore, the present invention is concerned with new 3-aminopyrazolo-heterocyclic compounds.

Thermal Rearrangements of Cyclic Amine Ylides. III. Intramolecular Cyclization of 2-Ethynylpyridine N-Imides to 3-Azaindolizine Derivatives

Treatment of the N-aminopyridinium salts (5a-e) prepared from 2-ethynylpyridines (4) with potassium carbonate resulted in an intramolecular cyclization to give the corresponding 3-azaindolizines (6) (pyrazolopyridines), presumably via the ionic in

Rearrangement of 2-Ethynylpyridinium N-Imides to Pyrazolopyridines

Pyrazolopyridines (6) are obtained from the N-amino-2-ethynylpyridinium salts (5) on treatment with base.