76943-47-0

Basic information

• Product Name: Pyrazolo[1,5-a]pyridin-2-ylmethanol
• Synonyms: PYRAZOLO[1,5-A]PYRIDIN-2-YL-METHANOL;Pyrazolo[1,5-a]pyridine-2-Methanol;(H-pyrazolo[1,5-a]pyridin-2-yl)Methanol
• CAS NO: 76943-47-0
• Molecular Formula: C₈H₈N₂O
• Molecular Weight: 148.16
• Mol File: 76943-47-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Density: 1.26 g/cm³
• Refractive Index: 1.64
• PKA: 13.61±0.10(Predicted)
• CAS DataBase Reference: Pyrazolo[1,5-a]pyridin-2-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazolo[1,5-a]pyridin-2-ylmethanol(76943-47-0)
• EPA Substance Registry System: Pyrazolo[1,5-a]pyridin-2-ylmethanol(76943-47-0)

Safety Data

• Hazardous Substances Data: 76943-47-0(Hazardous Substances Data)

Usage

General Description

Pyrazolo[1,5-a]pyridin-2-ylmethanol is a chemical compound with a unique molecular structure that includes a pyrazole ring fused to a pyridine ring. It is a yellow to brown solid at room temperature and is commonly used in chemical research and drug development. Pyrazolo[1,5-a]pyridin-2-ylmethanol has diverse potential pharmacological activities, including antimicrobial, anti-inflammatory, and antiviral properties. It has also been studied for its potential as a building block in the synthesis of pharmaceuticals. Additionally, Pyrazolo[1,5-a]pyridin-2-ylmethanol has shown promise as a potential drug candidate for the treatment of various diseases, making it an important chemical for further biomedical research and development.

InChI:InChI=1/C8H8N2O/c11-6-7-5-8-3-1-2-4-10(8)9-7/h1-5,11H,6H2

Upstream product

• 63237-87-6 pyrazolo[1,5-a]pyridine-2,3-dicarboxylic acid 
• 5825-71-8 pyrazolo<1,5-a>pyridine-2,3-dicarboxylic acid dimethyl ester 
• 25275-41-6 N-iminopyridinium ylide 
• 110-86-1 pyridine 
• 63237-88-7 pyrazolo[1,5-a]pyridine-2-carboxylic acid 
• 76943-44-7 2,4,6-Trimethyl-benzenesulfonate1-amino-2-(3-hydroxy-prop-1-ynyl)-pyridinium; 

Downstream Products

• 885275-10-5 pyrazolo[1,5-a]pyridine-2-carbaldehyde 
• 1201688-43-8 2-(1-methyl-4-phenyl-1H-imidazol-2-ylsulfanylmethyl)-pyrazolo[1,5-a]pyridine 

Relevant articles and documents

COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).

SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel spiro-oxadiazoline compounds that are suitable as agonists or partial agonists of a7-nAChR, and pharmaceutical compositions of the same, methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering a spiro-oxadiazoline cx7-nAChR agonist or partial agonist, to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINES, THEIR PREPARATION AND USE AS MEDICAMENTS

The present invention relates to new substituted pyrazolo[1,5-a]pyridine having a great affinity for sigma receptors, especially sigma-1 receptor, as well as to the process for the preparation thereof, to compositions comprising them, and to their use as medicaments.