76983-11-4Relevant academic research and scientific papers
Microwave-assisted synthesis of 2(1H)-pyridones and their glucosides as cell proliferation inhibitors
Al-Neyadi, Shaikha S.,Hassan, Ahmed H.,Abdou, Ibrahim M.
experimental part, p. 120 - 134 (2011/10/09)
A new series of substituted 2(1H)-pyridones (4a-i) and their glucosides (5, 6a-e) were prepared as potential agents against leukemia (HL-60) cells. Glucosides (5,6a-e) were synthesized using three independent methods. Microwave protocol as an ecologically
Reactions of α,β-Unsaturated Ketones with Cyanoacetamide
Al-Hajjar, Farouk H.,Jarrar, Adil A.
, p. 1521 - 1525 (2007/10/02)
3-Aryl-1-phenyl-2-propen-1-ones Ia-f and aroylphenylacetylenes Va-d reacted under reflux for 3 hours with cyanoacetamide in the presence of sodium ethoxide to give the corresponding 4-aryl-3-cyano-6-phenyl-2-(1H)pyridones VI.However, when ketones Ia-e wer
