76988-73-3Relevant academic research and scientific papers
2-Benzazepines. 6. Synthesis and Pharmacological Properties of the Metabolites of 9-Chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine
Trybulski, Eugene J.,Fryer, R. Ian,Reeder, Earl,Walser, Armin,Blount, John
, p. 1596 - 1601 (2007/10/02)
The 2-benzazepine 9-chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine (1) has been selected for development as an anxiolytic agent.In support of this program, we have confirmed by chemical synthesis the structures of three in vitro (rat liver hom
2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents
Trybulski, Eugene J.,Benjamin, Louis E.,Earley, James V.,Fryer, R. Ian,Gilman, Norman W.,et al.
, p. 1589 - 1596 (2007/10/02)
A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepine-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different
