769944-71-0

Basic information

• Product Name: 3-(4-broMophenyl)piperidin-2-one
• Synonyms: 3-(4-broMophenyl)piperidin-2-one;2-Piperidinone, 3-(4-bromophenyl)-;3-(4-bromophenyl)-2-Piperidinone
• CAS NO: 769944-71-0
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 254.12308
• Mol File: 769944-71-0.mol

Chemical Properties

• Boiling Point: 416.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.416±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 16.07±0.40(Predicted)
• CAS DataBase Reference: 3-(4-broMophenyl)piperidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-broMophenyl)piperidin-2-one(769944-71-0)
• EPA Substance Registry System: 3-(4-broMophenyl)piperidin-2-one(769944-71-0)

Safety Data

• Hazardous Substances Data: 769944-71-0(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry and Drug Discovery:
3-(4-bromophenyl)piperidin-2-one is utilized as a chemical scaffold for the development of new pharmaceutical agents. Its unique structure allows for the modulation of biological targets and receptors, which is crucial in the discovery of novel therapeutics.
Used in Neuroscience Research:
In the field of neuroscience, 3-(4-bromophenyl)piperidin-2-one is used as a research tool to explore its potential psychotropic properties. Its capacity to interact with the nervous system makes it a candidate for studies on mental health and related disorders.
Used in Pain Management:
3-(4-bromophenyl)piperidin-2-one is employed in the investigation of its analgesic properties. Its potential to alleviate pain makes it an object of interest for research into new treatments for chronic and acute pain conditions.

Upstream product

• 14062-25-0 Ethyl 4-bromophenylacetate 
• 1362192-80-0 6-amino-3-(4-bromo-phenyl)-hexanoic acid ethyl ester hydrochloride 

Downstream Products

• 769944-72-1 3-(4-bromo-phenyl)-piperidine 

Relevant articles and documents

POLY(ADP-RIBOSE) POLYMERASE INHIBITOR, PREPARATION METHOD AND USE

Disclosed are a compound as shown in general formula I, a pharmaceutically acceptable salt, an isomer or a mixture thereof, and a solvate, a polymorph, a stable isotope derivative or a prodrug thereof. The compound of the present disclosure has comparatively strong PARP inhibitory activity and can be used for treating diseases associated with PARP, such as cancers and inflammatory diseases.

A Niraparib intermediate (S)-3 - (4 - bromophenyl) piperidine preparation method (by machine translation)

The invention discloses a Niraparib intermediate (S)- 3 - (4 - bromophenyl) piperidine of preparation method, the method using the bromo ethyl acetate with N - boc - 3 - amino propyl bromide in alkali under the action of the nucleophilic reaction, ring un

2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES

A pyrimidone derivative having tau protein kinase 1 inhibitory activity which is represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof; useful for prventive and/or therapeutic treatment of diseass such as neurodegenerative diseases (e.g. Alzheimer disease); wherein Q represents CH or nitrogen atom; R represents a C1-C12 alkyl group; the ring of Formula (I): represents piperazine ring or piperidine ring; each X independently represents a C1-C8 alkyl group, an optionally partially hydrogenated C6-C10 aryl ring, an indan ring or the like; m represents an integer of 1 to 3; each Y independently represents a halogen atom, a hydroxy group, a cyano group, a C1-C6 alkyl group or the like; n represents an integer of 0 to 8; when X and Y or two Y groups are attached on the same carbon atom, they may combine to each other to form a C2-C6 alkylene group.