769944-72-1

Basic information

• Product Name: Piperidine, 3-(4-bromophenyl)-
• Synonyms: Piperidine, 3-(4-bromophenyl)-;3-(4-Bromophenyl)piperidine;3-(4-Bromophenyl)
• CAS NO: 769944-72-1
• Molecular Formula: C₁₁H₁₄BrN
• Molecular Weight: 240.14
• Mol File: 769944-72-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 310.9 °C at 760 mmHg
• Flash Point: 141.8 °C
• Appearance: /
• Density: 1.313
• Refractive Index: 1.553
• Storage Temp.: 2-8°C
• PKA: 9.90±0.10(Predicted)
• CAS DataBase Reference: Piperidine, 3-(4-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 3-(4-bromophenyl)-(769944-72-1)
• EPA Substance Registry System: Piperidine, 3-(4-bromophenyl)-(769944-72-1)

Safety Data

• Hazardous Substances Data: 769944-72-1(Hazardous Substances Data)

Usage

General Description

Piperidine, 3-(4-bromophenyl)- is a chemical compound typically used as an intermediate in the synthesis of other organic compounds. Piperidine, 3-(4-bromophenyl)- is classified under the category of phenylpiperidines, signifying that it has a piperidine substituted by a phenyl group. The presence of the bromophenyl substituent at the 3rd position of the piperidine ring gives this compound its characteristic properties. It's commonly used in the field of drug synthesis and development, particularly in pharmaceuticals and medicinal chemistry due to its versatility and reactivity. As with most chemicals, careful handling is crucial as it can pose risks and safety hazards.

InChI:InChI=1/C11H14BrN/c12-11-5-3-9(4-6-11)10-2-1-7-13-8-10/h3-6,10,13H,1-2,7-8H2

Upstream product

• 1692-25-7 3-pyridylboronic acid 
• 589-87-7 1,4-bromoiodobenzene 
• 129013-83-8 3-(4-bromophenyl)pyridine 
• 769944-71-0 3-(4-bromophenyl) piperidin-2-one 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 1008-88-4 3-phenylpyridine 
• 3973-62-4 3-phenylpiperidine 

Downstream Products

• 1338544-06-1 tert-butyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxylate 
• 1335523-82-4 4-(3S-piperidine-3-yl)bromobenzene 
• 1476776-55-2 (S)-3-(4-bromophenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 1196713-67-3 2-[4-((3S)-(tertbutoxycarbonyl)piperidin-3-yl)phenyl]-2H-indazole-7-carboxylic acid methyl ester 
• 769944-73-2 tert-butyl 3-(4-bromophenyl)piperidine-1-carboxylate 

Relevant articles and documents

INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR

Disclosed is a type of indolo heptamyl oxime compounds as a PARP inhibitor. Specifically disclosed are a compound as represented by formula (II) and a pharmaceutically acceptable salt thereof.

Preparation method of niraparib tosilate monohydrate

The invention discloses a preparation method of a compound 2-[4-((3S)-3-piperidyl)phenyl]-2H-indazole-7-formamide tosilate monohydrate. The method includes: carrying out Ulman reaction on 1H-indazole-7-methyl formate and (S)-3-(4-halogenophenyl)piperidine-1-tert-butyl formate to prepare 2-[4-((3S)-3-piperidyl)phenyl]-2H-indazole-7-methyl formate, then under the conditions of ammonia gas and p-toluenesulfonic acid, preparing 2-[4-((3S)-3-piperidyl)phenyl]-2H-indazole-7-formamide tosilate monohydrate. The invention aims to avoid the disadvantages of existing methods, shortens the preparation route, and provides the preparation method of the 2-[4-((3S)-3-piperidyl)phenyl]-2H-indazole-7-formamide tosilate monohydrate with high chiral purity, and the method has the characteristics of mild reaction and easy operation.

LINCOSAMIDE DERIVATIVE, AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT

An objective of the present invention is to provide compounds of formula (I) or their pharmacologically acceptable salts or solvates wherein A represents aryl while R1 represents a five- or six-membered monocyclic heterocyclic group, or A represents a four- to six-membered monocyclic heterocyclic group while R1 represents aryl or a five- or six-membered monocyclic heterocyclic group; R2 represents a hydrogen atom or C1-6 alkyl; R3 represents C1-6 alkyl or C3-6 cycloalkyl-C1-4 alkyl; R4, R5, and R6 represent a hydrogen atom; R7 represents C1-6 alkyl; and m is 1 to 3. The compounds are novel lincosamide derivatives that have a potent activity against resistant Streptococcus pneumoniae. Further, the compounds are usable as antimicrobial agents and are useful for preventing or treating bacterial infectious diseases.