769965-93-7

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 443-69-6 5-fluoro-1H-indole-2,3-dione 
• 522612-15-3 5-fluoro-1-(4-methoxybenzyl)-1H-indole-2,3-dione 

Downstream Products

• 769965-95-9 5′-fluorospiro[cyclopropane-1,3′-indoline]-2′-one 
• 913179-36-9 5’-fluorospiro[cyclopropane-1,3’-indoline] 
• 769965-94-8 5-fluoro-1-(4-methoxy-benzyl)-siprocyclopropyloxindole 

Relevant academic research and scientific papers

Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors

We report a novel series of noncovalent inhibitors of cathepsin S. The synthesis of the peptidomimetic scaffold is described and structure-activity relationships of P3, P1, and P1′ subunits are discussed. Lead optimization to a non-peptidic scaffold has r

INHIBITORS OF CATHEPSIN S

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.

INHIBITORS OF CATHEPSIN S

The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.