77007-12-6

Upstream product

• 1849-86-1 N-phenyl-N'-(benzothiazol-2-yl)thiocarbamide 
• 92969-20-5 1-benzothiazol-2-yl-2-ethyl-3-phenyl-isothiourea 
• 136-95-8 2-amino-benzthiazole 
• 64195-74-0 2-ethyl-1-phenyl-3-(phenyl-thiocarbamoyl)-isothiourea 
• 103-72-0 phenyl isothiocyanate 
• 1009735-07-2 C₁₅H₁₃N₃S₂ 

Relevant academic research and scientific papers

A synthetic method to access symmetric and non-symmetric 2-(N,N'-disubstituted)guanidinebenzothiazoles

Symmetric and non-symmetric 2-(N-H, N-methyl, N-ethylenyl and N-aryl)guanidinebenzothiazoles were synthesized from the reaction of ammonia, methylamine, pyrrolidine and aniline with dimethyl benzo[d]thiazol-2-yl- carbonodithioimidate (5) as intermediate. The products were characterized by 1H-, 13C-NMR spectroscopy and three of them by X-ray diffraction analysis. HN-phenyl protons formed intramolecular hydrogen bonds that assist the stereochemistry of the second substituent, whereas the HN-alkyl protons were involved in intermolecular hydrogen bonding.