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2-(2,5-dibromo-thiophen-3-yl)acetic acid is a chemical compound characterized by its molecular formula C6H4Br2O2S. It features a thiophene ring with two bromine atoms at the 2nd and 5th positions, and an acetic acid group attached at the 3rd position. 2-(2,5-dibromo-thiophen-3-yl)acetic acid is known for its potential applications in the synthesis of various organic compounds and pharmaceuticals, particularly those involving halogenated heterocycles. Due to its unique structure, it can be used as an intermediate in the preparation of complex molecules, offering a range of reactivity due to the presence of both bromine and carboxylic acid functional groups.

77014-10-9

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77014-10-9 Usage

Derivative of thiophene

2-(2,5-dibromo-thiophen-3-yl)acetic acid is a derivative of thiophene, a five-membered heterocyclic compound.

Commonly used in organic chemistry research

The compound is widely used in the field of organic chemistry for various research purposes.

Ability to modify and interact with biological molecules

2-(2,5-dibromo-thiophen-3-yl)acetic acid is known for its ability to modify and interact with biological molecules.

Potentially useful for pharmaceutical and medical applications

Because of its ability to interact with biological molecules, the compound is potentially useful for pharmaceutical and medical applications.

Building block in the synthesis of more complex organic molecules

The compound has been studied for its potential as a building block in the synthesis of more complex organic molecules.

Investigated for properties in materials science

2-(2,5-dibromo-thiophen-3-yl)acetic acid has been investigated for its properties in materials science.

Explored for potential use in the development of new materials

The compound is being explored for potential use in the development of new materials with specific properties.

Check Digit Verification of cas no

The CAS Registry Mumber 77014-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,0,1 and 4 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77014-10:
(7*7)+(6*7)+(5*0)+(4*1)+(3*4)+(2*1)+(1*0)=109
109 % 10 = 9
So 77014-10-9 is a valid CAS Registry Number.

77014-10-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,5-dibromo-thiophen-3-yl)acetic acid

1.2 Other means of identification

Product number -
Other names 2,5-dibromo-3-thienylacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77014-10-9 SDS

77014-10-9Upstream product

77014-10-9Relevant academic research and scientific papers

Fluorescent micellar nanoparticles by self-assembly of amphiphilic, nonionic and water self-dispersible polythiophenes with "hairy rod" architecture

Cianga, Luminita,Bendrea, Anca-Dana,Fifere, Nicusor,Nita, Loredana Elena,Doroftei, Florica,Ag, Didem,Seleci, Muharrem,Timur, Suna,Cianga, Ioan

, p. 56385 - 56405 (2015/02/18)

Polymers with "hairy-rod" architecture having oligo/polythiophene (PTh) as main chain and poly (ethylene glycol) (PEG) (Mn = 2000) as flexible side chains were obtained by combining the "macromonomer technique" with specific methods for the syn

Synthesis and characterization of alanine functionalized oligo/polythiophenes

McTiernan, Christopher D.,Chahma, M'Hamed

experimental part, p. 1417 - 1423 (2010/09/17)

The synthesis and characterization of a series of monothiophenes and terthiophenes bearing amino acids are reported. The reaction of a thiophene, substituted in position 3 by either a carboxylic acid or an acetic acid moiety, with an alanine methyl ester in the presence of hydroxybenzotriazole (HOBt) and N,N′-dicyclohexylcarbodiimide (DCC) affords several mono/terthiophene- alanine methyl esters. The latter were deprotected to form the corresponding carboxylic acids. Terthiophenes have been prepared in good yields via a Stille cross coupling reaction, using a dibromothiophene-alanine methyl ester and tri-butyl stannyl thiophene. The newly prepared monomers are very stable in air and in the presence of organic solvents. The optical and electrochemical properties of the monomers and their corresponding polymers were also examined using cyclic voltammetry and indium tin oxide (ITO) electrodes.

Synthesis and properties of light-emitting polythiophene derivatives bearing terphenyl mesogenic pendant

Chen, Lie,Chen, Yiwang,Zhou, Weihua,Li, Fan,He, Xiaohui,Tang, Ben Zhong

experimental part, p. 70 - 83 (2011/05/03)

A series of polythiophenes containing terphenyl mesogenic side chain at the third position through ester bonding was synthesized by dehalogenative polycondensation. The thiophene monomers 2,5-bromo-3-{[(4-(4'-cyano) terphenyloxy)carbonyl]-methyl]}-thiophene [M(CN)] and 2,5-bromo-3-{[(4-(4'- methoxy)terphenyloxy)-carbonyl]methyl}-thiophene [M(OCH3)] were prepared via Suzuki reation and esterification reactions, in sequence. The structures and properties of the monomers and polymers were characterized and evaluated with nuclear magnetic resonance, infrared spectroscopy, thermogravimetry, differential scanning calorimetry, polarized optical microscopy, ultraviolet spectroscopy, and photoluminescence. All of the polymers were stable, losing little of their weights when heated to 300°C. The polymers showed good solubility and could be dissolved in common solvents such as CHCl3, THF, DMF, etc. The monomers exhibited enantiotropic SmAd phases with a bilayer arrangement in the heating and cooling processes. Due to short spacer methylene ester between the bulk terphenyl mesogenic side chain and rigid polythiophene main chain, the polymers could not exhibit liquid crystallinty at elevated temperature. The existence of the chromophoric terphenyl core endows the polymers with high photoluminescence. When their CH2Cl2 solutions were photoexcited, the polymers emitted a strong UV light about 400nm.

Synthesis of Polythiophene Derivatives Bearing Ferroelectric Liquid Crystalline Substituents

Goto, Hiromasa,Dai, Xiaoman,Narihiro, Harunori,Akagi, Kazuo

, p. 2353 - 2362 (2007/10/03)

A chiral liquid crystalline (LC) substituent with a fluorine-containing asymmetric moiety was introduced into the 3-position of a thiophene ring. Polymerizations of 2,5-dibrominated thiophene derivatives were carried out through dehalogenative polycondensations. Polythiophene derivatives thus prepared were fusible and soluble in ordinary organic solvents. An absorption band was observed in the range of 400-415 nm. Phase transition behaviors of the polymers and monomers were examined by differential scanning calorimetry, polarizing optical microscopy, and X-ray diffraction analysis. The polymers showed several types of smectic phases in the heating and cooling processes. Additionally, one of the polymers exhibited a striated fan-shaped texture when observed with a polarizing optical microscope. This is attributed to the formation of chiral smectic C (SmC*) phase, which is necessary property to ferroelectricity. Ferroelectric behavior was confirmed by examining the temperature dependence of the dielectric constant of the polymer.

Synthesis and properties of liquid crystalline polythiophene and polythienylenevinylene derivatives

Osaka, Itaru,Goto, Hiromasa,Itoh, Kikuo,Akagi, Kazuo

, p. 339 - 346 (2007/10/03)

Liquid crystalline polythiophene (LC-PTs) and polythienylenevinylene (LC-PTVs) derivatives with various length of methylene spacer in the LC substituents were synthesized. LC-PTs were prepared through dehalogenative polycondensation using Ni(0) complex, a

STUDIES ON HETEROCYCLIC COMPOUNDS VI. Synthesis of Thiophene Isoesters of Protoberberine Alkaloids

Jeganathan, S.,Srinivasan, M.

, p. 125 - 138 (2007/10/02)

Synthesis of thiophene isosters of protoberberine alkaloids (6, 12, 19) is described.The Mannich type reaction of the tetrahydroisoquinolines (5, 11) and the thienopyridine (18) with formaldehyde in glacial acetic acid afforded the title compounds.Cyclization of the tetrahydroisoquinoline derivative (23) failed to furnish the D-ring protoberberine isoster (25), but gave an unexpected product, the oxazepinoisoquinoline derivative (24).The conversion of the compound (24) to the 2-substituted isoquinoline (27) is also described.

Studies on Heterocyclic Compounds : Part V - Synthesis of 6-Acetyl-1,2-dimethoxy-4H-5,6,6a,7-tetrahydrobenzothienoquinoline

Jeganathan, S.,Srinivasan, M.

, p. 1028 - 1030 (2007/10/02)

Photosynthesis of 6-acetyl-1,2-dimethoxy-4H-5,6,6a,7-tetrahydrobenzothienoquinoline (9), which is a D-ring thiophene isoster of aporphine alkaloid, is described.The synthetic sequence involves Bischler-Napieralski reaction to the isoquinoline s

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