77039-78-2

Basic information

• Product Name: 2-Chromanecarbonylchloride
• Synonyms: 2H-1-Benzopyran-2-carbonyl chloride, 3,4-dihydro- (9CI);Chromane-2-carbonyl chloride
• CAS NO: 77039-78-2
• Molecular Formula: C₁₀H₉ClO₂
• Molecular Weight: 196.63026
• Product Categories: ACIDHALIDE
• Mol File: 77039-78-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 292.4°C at 760 mmHg
• Flash Point: 108.9°C
• Appearance: /
• Density: 1.281g/cm³
• Vapor Pressure: 0.00184mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 2-Chromanecarbonylchloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chromanecarbonylchloride(77039-78-2)
• EPA Substance Registry System: 2-Chromanecarbonylchloride(77039-78-2)

Safety Data

• Hazardous Substances Data: 77039-78-2(Hazardous Substances Data)

Usage

General Description

2-Chromanecarbonylchloride is a chemical compound with the formula C10H7ClO2. It is a carbonyl chloride derivative of 2-chromene, and is often used as a reagent in organic synthesis. 2-Chromanecarbonylchloride is a colorless liquid at room temperature and is highly reactive due to the presence of the carbonyl chloride functional group. 2-Chromanecarbonylchloride is primarily used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is known for its ability to undergo nucleophilic acyl substitution reactions, making it a valuable tool for chemists in the development of new molecules and compounds. Additionally, it can be used as a building block in the synthesis of various heterocyclic compounds and organic intermediates.

InChI:InChI=1/C10H9ClO2/c11-10(12)9-6-5-7-3-1-2-4-8(7)13-9/h1-4,9H,5-6H2

Upstream product

• 4940-39-0 acide chromone carboxylique-2 
• 51939-71-0 chroman-2-carboxylic acid 

Downstream Products

• 81816-78-6 Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone 
• 3990-58-7 chroman-2-ylcarboxamide 
• 81816-79-7 Chroman-2-yl-(4-o-tolyl-piperazin-1-yl)-methanone 
• 345934-98-7 Chroman-2-carboxylic acid [2-(4-methoxy-phenyl)-ethyl]-amide 
• 3990-59-8 2-(aminomethyl)chromane 
• 81816-83-3 1-Chroman-2-ylmethyl-4-o-tolyl-piperazine 
• 81816-82-2 N¹-(2'-aminomethylchromanyl)-N⁴-phenylpiperazine 
• 99290-94-5 1-Chroman-2-ylmethyl-piperidine 

Relevant articles and documents

ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF

The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.

SUBSTITUTED AMINOMETHYLTETRALINS AND THEIR HETEROCYCLIC ANALOGUES

For binding 5-HT 1 receptors and thereby treating central nervous system disorders, novel substituted aminomethyltetralins and their heterocyclic analogues of the formula STR1 in which Z--denotes a group of the formula STR2 R 1, E and F can be hydrogen or other radicals, or salts thereof.

Pharmacomodulation d'adrenolytiques α en serie benzopyrannique

Pharmacomodulation of α-adrenergic blocking agents by a series of benzopyrans.The N-methylpiperidine fragment was associated with four oxygenated heterocycles of the benzopyran ring system.Two different synthesis pathways were used in each case.Twenty intermediate derivatives and four aminomethylated derivatives whose structures were established by spectroscopic data are described.The pharmacological investigation demonstrates the interest of these compounds on the α-adrenergic receptors in light of their activities and selectivities. α1-adrenergic blocking agents / α2-adrenergic blocking agents / piperidinomethyl chromone, chromene and chromane