2-Chromanecarbonylchloride

Base Information

• Chemical Name: 2-Chromanecarbonylchloride
• CAS No.: 77039-78-2
• Molecular Formula: C10H9 Cl O2
• Molecular Weight: 196.63026
• Hs Code.: 2932999099
• Mol file: 77039-78-2.mol

Synonyms:2-(Chlorocarbonyl)-3,4-dihydro-2H-1-benzopyran;3,4-Dihydro-1-benzopyran-2-carbonyl chloride; 3,4-Dihydro-2H-1-benzopyran-2-carbonylchloride; Chroman-2-carbonyl chloride

Chemical Property of 2-Chromanecarbonylchloride

Chemical Property:

• Vapor Pressure: 0.00184mmHg at 25°C
• Refractive Index: 1.557
• Boiling Point: 292.4°C at 760 mmHg
• Flash Point: 108.9°C
• PSA: 26.30000
• Density: 1.281g/cm³
• LogP: 2.14560

Purity/Quality:

98%Min ^*data from raw suppliers

Chromane-2-carbonyl chloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chromanecarbonylchloride

There total 3 articles about 2-Chromanecarbonylchloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

chroman-2-carboxylic acid (51939-71-0) → 2,3-dihydro-4H-benzopyran-2-carboxylic acid chloride (77039-78-2)

Guidance literature:

With thionyl chloride; In benzene; for 2.5h; Heating;

DOI:10.1021/jm00371a003

Reference yield:

acide chromone carboxylique-2 (4940-39-0) → 2,3-dihydro-4H-benzopyran-2-carboxylic acid chloride (77039-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: 86 percent / thionyl chloride / cyclohexane / 6 h / Heating

With thionyl chloride; hydrogen; palladium on activated charcoal; In cyclohexane;

DOI:10.1016/0223-5234(87)90294-7

Reference yield:

→ 2,3-dihydro-4H-benzopyran-2-carboxylic acid chloride (77039-78-2)

Guidance literature:

aus entspr. Saeure;

DOI:10.1039/j29670000859

upstream raw materials:

chroman-2-carboxylic acid

acide chromone carboxylique-2

Downstream raw materials:

Chroman-2-yl-(4-phenyl-piperazin-1-yl)-methanone

chroman-2-ylcarboxamide

Chroman-2-yl-(4-o-tolyl-piperazin-1-yl)-methanone

Chroman-2-carboxylic acid [2-(4-methoxy-phenyl)-ethyl]-amide