77052-35-8Relevant academic research and scientific papers
METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF
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, (2011/06/25)
Disclosed are (N)-methanocarba adenine nucleosides, e.g., of the formula (I): as A3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein A, a, R2, and
2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A3 adenosine receptor-selective agonists
Tosh, Dilip K.,Chinn, Moshe,Yoo, Lena S.,Kang, Dong Wook,Luecke, Hans,Gao, Zhan-Guo,Jacobson, Kenneth A.
experimental part, p. 508 - 517 (2010/05/02)
We modified a series of (N)-methanocarba nucleoside 5′-uronamides to contain dialkyne groups on an extended adenine C2 substituent, as synthetic intermediates leading to potent and selective A3 adenosine receptor (AR) agonists. The proximal alk
The synthesis of N-substituted isothiazol-3(2H)-ones from N-substituted 3-benzoylpropionamides
Hamilakis, Stylianos,Kontonassios, Demetrios,Tsolomitis, Athanase
, p. 149 - 155 (2007/10/03)
N-Substituted isothiazol-3(2H)-ones can be easily prepared from N-substituted 3-benzoylpropionamides in two experimentally simple steps, in satisfactory overall yields. Reaction of the amides with excess thionyl chloride results in the formation of N-subs
Formation of 5-Aroyl-3-(2H)isothiazolones from the Reaction of 3-Aroylpropionamides with Thionyl Chloride (1)
Tsolomitis, A.,Sandris, C.
, p. 1645 - 1646 (2007/10/02)
Reaction of N-substitued-3-aroylpropionamides with excess thionyl chloride was found to give sulfurnitrogen heterocyclic compounds, which were characterized as 2-substituted-5-aroyl-3-(2H)isothiazolones.
