77063-12-8Relevant articles and documents
Thermoresponsive chlorambucil derivatives for tumour targeting
Clavel, Catherine M.,Zava, Olivier,Schmitt, Frederic,Halamoda Kenzaoui, Blanka,Nazarov, Alexey A.,Juillerat-Jeanneret, Lucienne,Dyson, Paul J.
supporting information; experimental part, p. 7124 - 7127 (2011/09/21)
Putting the heat on: Drugs that are essentially inactive at 37°C and are active under mild hyperthermia can be synthesized by modification of chlorambucil with thermoresponsive groups (see picture; C gray, Cl green, F yellow, H white, N blue, O red). This