770696-44-1Relevant academic research and scientific papers
Synthesis and SAR of adatanserin: Novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT2 activity as potential anxiolytic and antidepressant agents
Abou-Gharbia, Magid A.,Childers Jr., Wayne E.,Fletcher, Horace,McGaughey, Georgia,Patel, Usha,Webb, Michael B.,Yardley, John,Andree, Terrance,Boast, Carl,Kucharik Jr., Robert J.,Marquis, Karen,Morris, Herman,Scerni, Rosemary,Moyer, John A.
, p. 5077 - 5094 (2007/10/03)
Several novel functionalized adamantyl aryl- and heteroarylpiperazine derivatives were prepared and examined in various receptor binding and behavioral tests to determine their serotonin receptor activities. Many compounds demonstrated modest to high affi
