770745-89-6

Upstream product

• 1643-30-7 3-(4-bromophenyl)propionic acid 
• 433332-03-7 1-(3-benzyloxypropyl)-4-bromobenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 25574-11-2 3-(4-bromophenyl)propanol 
• 454678-96-7 4-[3-(benzyloxy)propyl]benzaldehyde diethyl acetal 
• 100-39-0 benzyl bromide 

Downstream Products

• 454678-94-5 4-[3-(Benzyloxy)propyl] benzyl alcohol 
• 1407506-23-3 4-[4-(3-fluoropropyl)benzyl]-L-glutamic acid 
• 1407507-02-1 di-tert-butyl N-(tert-butoxycarbonyl)-4-[4-(3-fluoropropyl)benzyl]-L-glutamate 
• 1407507-18-9 di-tert-butyl (4S)-N-(tert-butoxycarbonyl)-4-[4-(3-hydroxypropyl)benzyl]-L-glutamate 
• 1407507-25-8 1-[3-(benzyloxy)propyl]-4-(bromomethyl)benzene 
• 1407507-26-9 Di-tert-butyl (4S)-4-{4-[3-(benzyloxy)propyl]benzyl}-N-(tert-butoxycarbonyl)-L-glutamate 
• 1407506-24-4 di-tert-butyl (4S)-N-(tert-butoxycarbonyl)-4-{4-[3-(tosyloxy)propyl]benzyl}-L-glutamate 

Relevant academic research and scientific papers

RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING

This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).

Radiolabeled amino acids for diagnostic imaging

This invention relates to novel compounds suitable for labeling by 18F and to the corresponding 18F labeled compounds themselves, 19F-fluorinated analogues thereof and their use as reference standards, methods of preparing such compounds, compositions comprising such compounds, kits comprising such compounds or compositions and uses of such compounds, compositions or kits for diagnostic imaging by Positron Emission Tomography (PET).

FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF

The present invention provides fused heterocyclic derivatives represented by the general formula: wherein R1 represents H, halogen, OH, etc.; R2 represents H, halogen or an alkyl group; R3 and R4 represent H, OH, halogen, etc.; Q represents alkylene, etc.; ring A represents aryl or heteroaryl; and G represents or ???or pharmaceutically acceptable salts thereof, or prodrugs thereof, which exhibit an excellent inhibitory activity in human SGLT and are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications or obesity, pharmaceutical compositions comprising the same, and pharmaceutical uses thereof.

GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND MEDICINAL USE THEREOF

The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein one of Q and T represents a group represented by the general formula: while the other represents a lower alkyl group or a halo(lower alkyl) gr