770746-45-7Relevant academic research and scientific papers
[2+2] Photocycloadditions with chiral uracil derivatives: Access to all four stereoisomers of 2-aminocyclobutanecarboxylic acid
Fernandes, Carlos,Gauzy, Christine,Yang, Yi,Roy, Olivier,Pereira, Elisabeth,Faure, Sophie,Aitken, David J.
, p. 2222 - 2232 (2008/03/28)
Starting from a single, chiral, bicyclic derivative of uracil, all four stereoisomers of 2-aminocyclobutanecarboxylic acid have been prepared in enantiomerically pure form, using a synthetic sequence which begins with a key photochemical [2+2] cycloaddition reaction and includes a practical cis to trans β-amino acid isomerisation procedure. Georg Thieme Verlag Stuttgart.
Synthesis of (+)-(1S,2R) and (-)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids
Gauzy, Christine,Pereira, Elisabeth,Faure, Sophie,Aitken, David J.
, p. 7095 - 7097 (2007/10/03)
(+)-(1S,2R) and (-)-(1R,2S)-2-aminocyclobutane-1-carboxylic acids have been prepared in >97% ee and in 33% and 20% overall yields starting from a single, chiral, bicyclic compound perceived as a chiral uracil equivalent. Construction of the cyclobutane ri
