77077-60-2 Usage
General Description
2,5-diphenylthiazol-4-amine is a chemical compound with a molecular formula C17H13N3S. It is a thiazole derivative with two phenyl groups attached to the thiazole ring. 2,5-diphenylthiazol-4-aMine has been extensively studied for its potential pharmaceutical and industrial applications. It has been investigated for its antitumor and antiproliferative properties. Additionally, it has been used as a building block in the synthesis of various organic compounds. The compound has also been studied for its potential use in the development of fluorescent sensors and organic light-emitting diodes. Its structure and properties make it a versatile and valuable compound in the field of organic chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 77077-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,0,7 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 77077-60:
(7*7)+(6*7)+(5*0)+(4*7)+(3*7)+(2*6)+(1*0)=152
152 % 10 = 2
So 77077-60-2 is a valid CAS Registry Number.
77077-60-2Relevant academic research and scientific papers
4-Hydroxythiazole Inhibitors of 5-Lipoxygenase
Kerdesky, Francis A. J.,Holms, James H.,Moore, Jimmie L.,Bell, Randy L.,Dyer, Richard D.,et al.
, p. 2158 - 2165 (2007/10/02)
4-Hydroxythiazoles have been identified as potent inhibitors of 5-lipoxygenase in vitro exhibiting IC50's of less than 1 μM.An investigation of structure-activity relationships showed that the most potent inhibitors of this series are the 5-phenyl derivatives.The corresponding thiazolidin-4-one analogues were found to be relatively inactive.The 4-hydroxythiazoles were active inhibitors against 5-lipoxygenase in both intact rat polymorphonuclear leukocytes and human whole blood.The compounds were also selective inhibitors of 5-lipoxygenase, displaying only weak activity against other related enzymes, cyclooxygenase and 12- and 15-lipoxygenase.
