77123-91-2

Usage

Uses

Used in Pharmaceutical Industry:
DIBENZO[1,2]OXATHIIN 6-OXIDE is used as an antitumor and anti-inflammatory agent for its potential therapeutic effects in treating various diseases.
Used in Organic Synthesis:
DIBENZO[1,2]OXATHIIN 6-OXIDE is used as a building block in the synthesis of pharmaceuticals and other organic compounds, contributing to the development of new chemical entities with potential applications in medicine and other fields.

InChI:InChI=1/C12H8O2S/c13-15-12-8-4-2-6-10(12)9-5-1-3-7-11(9)14-15/h1-8H

Upstream product

• 1016-05-3 dibenzothiophene sulfone 
• 1013-23-6 Dibenzothiophene sulfoxide 

Downstream Products

• 1806-29-7 2,2'-dihydroxybiphenyl 
• 90-43-7 2-Phenylphenol 
• 132-64-9 dibenzofuran 
• 132-65-0 dibenzothiophene 
• 1016-05-3 dibenzothiophene sulfone 

Relevant academic research and scientific papers

Unique Thia-Baeyer–Villiger-Type Oxidation of Dibenzothiophene Sulfoxides Derivatives

The present research has demonstrated that selective C?S bond cleavages of dibenzothiophene and its derivatives are feasible by thia-Baeyer–Villiger type oxidation, i. e. the oxygen insertion process within a sulfoxide-carbon linkage, in the presence of porphyrin iron (III) and by ultraviolet irradiation originating from sunlight, high pressure Hg-lamp or residentially germicidal ultraviolet lamp under very mild conditions. This reaction with tert-butylhydroperoxide at 30.0 °C leads to dibenzo[1,2]oxathiin-6-oxide (PBS) in 83.2 % isolated yield or its hydrated products, 2-(2-hydroxyphenyl)-benzenesulfinic derivatives (HPBS) in near 100 % yield based HPLC data. PBS and HPBS are a type of biological products detected on the C?S bond cleavage step through various oxidative biodesulfurization (OBDS) pathways, and are useful synthetic intermediates and fine chemicals. These observations may contribute on understanding delicately molecular aspect of OBDS in the photosynthesis system, expanding the C-S cleavage chemistry of S-heterocyclic compounds and approaching toward biomemic desulfurization with respect to converting sulfur contaminants to chemically beneficial blocks as needed and performing under the ambient conditions.

Preparation, Characterization, and Flash Vacuum Pyrolysis of Dibenzoxathiin 6-Oxide (Biphenylene Sultine)

Dibenzoxathiin 6-oxide (2), previously proposed as an intermediate in the pyrolysis of dibenzothiophene 5,5-dioxide (1), has been prepared by the treatment of 1 with KOH in the presence of crown ether followed by an acid workup.The likely intermediacy of the dipotassium salt of 2-(2-hydroxyphenyl)benzenesulfinic acid is demonstrated.Flash pyrolysis of 2 gives dibenzofuran and dibenzothiophene in essentiallly the same ratio as when they are formed in the pyrolysis of 1, suggesting that both products arise from the intermediacy of 2.