77129-72-7Relevant academic research and scientific papers
A study of the Willgerodt-Kindler reaction to obtain thioamides and α-ketothioamides under solvent-less conditions
Valdez-Rojas, Jose Ernesto,Rios-Guerra, Hulme,Ramirez-Sanchez, Alma Leticia,Garcia-Gonzalez, Guadalupe,Alvarez-Toledano, Cecilio,Lopez-Cortes, Jose Guadalupe,Toscano, Ruben A.,Penieres-Carrillo, Jose Guillermo
supporting information; experimental part, p. 567 - 573 (2012/08/08)
In this paper, the results obtained in the synthesis of thioamides and α-ketothioamides by a modification of the Willgerodt-Kindler reaction, under solvent-free and noncatalyst conditions using IR energy as a source of activation, are presented. The use of IR energy in these reactions has been shown to lead to a mixture of thioamide and α-ketothioamide as the main products in most cases, with the latter predominating. The yields of α-ketothioamides from most of these reactions are better than those reported previously. To the best of our knowledge, this is the first time that IR energy has been applied to promote the Willgerodt-Kindler reaction.
Ultrasound-mediated willgerodt-kindler reactions: Non-thermal synthesis of thioacetamides
Mojtahedi, Mohammad M.,Alishiri, Tooba,Abaee, M. Saeed
experimental part, p. 1910 - 1915 (2011/10/08)
Non-thermal, solvent-free condensation of several aryl methyl ketones with amines and elemental sulfur is efficiently conducted using ultrasonic irradiation within short time periods. Consequently, various thioacetamides are conveniently synthesized. Simi
Reactions of N,N-(dialkyl)arylthioacetamides with dialkyl acetylenedicarboxylates
Kosterina, M. F.,Morzherin, Yu. Yu.,Tkachev, A. V.,Rybalova, T. V.,Gatilov, Yu. V.,Bakulev, V. A.
, p. 653 - 658 (2007/10/03)
2-(Alkoxycarbonylmethylidene)-4-aryl-5-(dialkylamino)thiophen-3(2H)-ones were synthesized by condensation of N,N-(dialkyl)arylthioacetamides with dialkyl acetylenedicarboxylates. Intermediate substituted vinylic sulfides were isolated. When heated or in t
Substituted 1,2,3-thia-diazole-4-thiolates
-
, (2008/06/13)
Intermediates useful for synthesis of cephalosporins are disclosed, which intermediates are concerned with 1,2,3-thiadiazole-4-thiolates and the preparation of such thiolates.
1,2,3-Thiadiazoles. I. Synthesis of Sodium (or Potassium) 1,2,3-Thiadiazole-4-thiolates via Thiocarbazonate Esters and N-Acylthiohydrazonate Esters
Lee, Ving J.,Curran, William V.,Fields, Thomas F.,Learn, Keith
, p. 1873 - 1891 (2007/10/02)
A general synthesis of 1,2,3-thiadiazole-4-thiolates 1 and their derivatives 2-3 by an extension of the Hurd-Mori 1,2,3-thiadiazole synthesis is described.Treatment of methyl (or ethyl) hydrazinocarboxylates 11 (thiocarbazonate es
Infrared spectra of several thiopiperidides and thiomorpholides
Cornea, Felicia,Cercasov, Cornelia,Ciureanu, Mariana
, p. 775 - 782 (2007/10/02)
Infrared spectra in the 1700-500 cm-1 region have been studied for several types of thiopiperidides (thiobenzoylpiperidides, thiocinnamoylpiperidides and phenylthioacetpiperidides) and for the corresponding thiomorpholides.Three characteristic thioamide bands were located and assigned.The behaviour of these bands on molecular complexing (with iodine as an electron acceptor) was used to support the assignments.The experimental data were discussed in terms of the theoretical results obtained by an HMO procedure.
