7713-78-2

Upstream product

• 1194790-84-5 methyl 4-methyl-3-oxo-5-phenyl-2,3-dihydro-1H-pyrazole-1-carboxylate 
• 18020-59-2 methyl 3-hydroxy-2-methylidene-3-phenylpropionate 
• 100-52-7 benzaldehyde 
• 82111-78-2 methyl 2-benzoylprop-2-enoate 
• 32742-19-1 methyl 2-benzoylpropionate 
• 10488-87-6 ethyl 2-benzoylpropionate 

Downstream Products

• 79994-66-4 3-phenyl-1,2,4-trimethylpyrazolin-3-one 
• 60065-20-5 4-chloro-4-methyl-5-phenyl-2,4-dihydro-pyrazol-3-one 
• 102539-48-0 4-bromo-4-methyl-5-phenyl-2,4-dihydro-pyrazol-3-one 
• 104296-57-3 2-acetyl-4-chloro-4-methyl-5-phenyl-2,4-dihydro-pyrazol-3-one 

Relevant academic research and scientific papers

Morita-Baylis-Hillman adducts as building blocks of heterocycles: a simple approach to 4-substituted pyrazolones, and mechanism investigation via ESI-MS(/MS)

Abstract We describe herein an efficient approach for the preparation of 4-substituted 2,3-dihydro-1H-pyrazol-3-ones starting from Morita-Baylis-Hillman adducts. These heterocycles were obtained in two or three steps as single isomers with moderate to goo

A simple approach to pyrazol-3-ones via diazenes

An efficient entry into pyrazol-3-ones is described starting from propenoic acids that were first transformed into the corresponding hydrazides. Oxidation of the hydrazides gave the diazenes and the latter cyclized to pyrazol-3-ones on treatment with ZrCl4. The methoxycarbonyl protection of the N-1 of the pyrazolone derivatives was easily removed under mild reaction conditions.