77134-22-6Relevant academic research and scientific papers
Triazolopyridines. Part 2. Preparation of 7-Substituted Triazolopyridines by Directed Lithiation
Jones, Gurnos,Sliskovic, D. Robert
, p. 967 - 972 (2007/10/02)
The lithiation reactions of 1,2,3-triazolopyridine (1) to give the 7-lithio-derivative (4; R = Li), and of its 7-methyl derivative (16) to give the 7-lithiomethyl compound, are described.These lithium derivatives react with electrophiles, notably a
[1,2,3]Triazolo[1,5-a]pyridine - a synthon for 6-substituted pyridine-2-carboxaldehydes
Jones, Gurnos,Sliskovic, D.Robert
, p. 4529 - 4530 (2007/10/02)
[1,2,3]Triazolo[1,5-a]pyridine (1) is lithiated in position 7; the lithio derivative is used to synthesize triazolopyridinyl alcohols (6) which can be converted into 6-substituted pyridine-2-aldehydes (3).
